A clinical method for the determination of serum gamma-glutamyl transpeptidase

Clinica Chimica Acta; International Journal of Clinical Chemistry
H TamaokiK Fujisawa

Abstract

A simple, highly sensitive and reproducible method for the assay of gamma-glutamyl transpeptidase (EC 2.3.2-) activity is introduced, using gamma-glutamyl-p-nitroanilide as a substrate and glycylglycine as an acceptor in 50 g/l of polyoxyethylene nonylphenol. Serum transpeptidase activity was assayed in 1080 healthy adults, the normal mean value being 14.8 mU/ml. The diagnostic evaluation of the enzyme in various hepatobiliary diseases is also discussed.

References

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Citations

Dec 8, 1980·Clinica Chimica Acta; International Journal of Clinical Chemistry·S MiyakeK Shimono
Jan 1, 1997·Drug Metabolism and Drug Interactions·S KocaoğluG Başdemir
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Related Concepts

Biliary Tract Diseases
Synthetic Detergent
Gamma-glutamyl transferase
Liver Dysfunction
Microchemistry
Spectrophotometry

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