Abstract
The aim was to develop a clinically useful patient risk score predictive for stent thrombosis (ST). Using readily available baseline clinical and angiographic characteristics, a Cox proportional hazards multivariate model was used to identify significant (p <0.10) predictors of ST through 1 year in 2,487 patients receiving a TAXUS Express (Boston Scientific Corp., Natick, Massachusetts) drug-eluting stent (DES) in the ARRIVE 1 registry. Hazard ratios of significant predictors were rounded to an integer value ranging from 2 to 5. These values were summed for a maximum possible score of 24. The model was validated using 1-year data from a similar DES data set (ARRIVE 2, n = 4,820 patients). The 8 significant predictors found were thienopyridine therapy discontinuation before 6 months, insulin-requiring diabetes, smoker at baseline, left main stent placement, multiple stent placement, lesion length >28 mm, moderate to severe lesion calcification, and reference vessel diameter <3 mm. Model discrimination was high, indicated by an area under the receiver-operator characteristic curve of 0.819. Stratification of patients into low-, medium-, and high-risk groups showed that ST developed in 0.8% of patients with a score <6, 3.6% of pat...Continue Reading
References
Jan 3, 2001·European Heart Journal·H HiokiK Ishikawa
Jul 27, 2002·Journal of the American College of Cardiology·Mandeep SinghCharanjit S Rihal
May 5, 2005·JAMA : the Journal of the American Medical Association·Ioannis IakovouAntonio Colombo
Jun 21, 2005·Journal of the American College of Cardiology·Andrew T L OngPatrick W Serruys
Mar 15, 2006·Circulation·Philip UrbanUNKNOWN e-Cypher Investigators
Jun 14, 2006·Circulation·John A SpertusDavid J Cohen
Jul 25, 2006·The American Journal of Cardiology·Duk-Woo ParkSeung-Jung Park
Dec 7, 2006·JAMA : the Journal of the American Medical Association·Eric L EisensteinRobert M Califf
Dec 19, 2006·Journal of the American College of Cardiology·Matthias PfistererUNKNOWN BASKET-LATE Investigators
May 2, 2007·Circulation·Donald E CutlipUNKNOWN Academic Research Consortium
May 10, 2007·JAMA : the Journal of the American Medical Association·Htut K WinUNKNOWN EVENT Registry Investigators
Jun 30, 2007·The American Journal of Cardiology·Ron WaksmanUNKNOWN REWARDS registry
Aug 7, 2007·Journal of the American College of Cardiology·Jacques MachecourtUNKNOWN EVASTENT Investigators
Dec 15, 2007·Circulation·Spencer B KingClyde W Yancy
Dec 15, 2007·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·UNKNOWN American College of Cardiology, UNKNOWN American Heart Association Task Force on Practice Guidelines
Sep 25, 2008·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·John M LasalaUNKNOWN ARRIVE 1 Participating Physicians
Citations
Feb 17, 2009·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Davide CapodannoCorrado Tamburino
Dec 24, 2011·Current Treatment Options in Cardiovascular Medicine·Julio F MarchiniKevin Croce
Jul 1, 2010·Cardiovascular Intervention and Therapeutics·Kunihiko KosugaTakafumi Tsuji
May 1, 2011·Cardiovascular Intervention and Therapeutics·Toshiharu FujiiYuji Ikari
Mar 23, 2011·Circulation·Kumaran KolandaiveluElazer R Edelman
Apr 12, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Hironori Kaneko, Mikihiro Kijima
Oct 20, 2010·Vascular Health and Risk Management·Juan V LlauAurelio Gómez-Luque
Feb 19, 2011·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Kenneth W BaranUNKNOWN ARRIVE Investigators
Sep 8, 2015·Progress in Cardiovascular Diseases·Kirk N Garratt
Sep 17, 2011·Journal of Interventional Cardiology·Hiroki ItoGregg W Stone
Oct 24, 2009·Internal Medicine Journal·C-L PohC-H Lee
Nov 8, 2011·Annales de cardiologie et d'angéiologie·G Lemesle, C Delhaye
May 30, 2009·Journal of the American College of Cardiology·Simon R DixonWilliam W O'Neill
Mar 1, 2012·International Journal of Cardiology·Fabrizio D'AscenzoGiuseppe Biondi-Zoccai
Aug 20, 2009·Angiology·Ayman El-MenyarJassim Al Suwaidi
Dec 25, 2009·Circulation. Cardiovascular Interventions·John M LasalaUNKNOWN ARRIVE 1 and ARRIVE 2 Participating Physicians
Aug 2, 2017·Circulation. Cardiovascular Interventions·Xavier Garcia-Moll
Dec 25, 2009·Circulation. Cardiovascular Interventions·Antonio Colombo, Robert T Gerber
Jan 7, 2016·Annals of Biomedical Engineering·Caroline C O'BrienElazer R Edelman
Oct 28, 2009·Platelets·A Carla ZomerMaarten-Jan Suttorp
Jul 24, 2021·The American Journal of Cardiology·Luca FranchinFabrizio D'Ascenzo