A clinical role of staging laparoscopy in patients with radiographically defined locally advanced pancreatic ductal adenocarcinoma

World Journal of Surgical Oncology
Sohei SatoiMasanori Kon

Abstract

The aim of current study is to verify usefulness of staging laparoscopy (stag-lap) for patient's selection and to find prognostic factors in patients with radiographically defined locally advanced (RD-LA) pancreatic ductal adenocarcinoma (PDAC). The LA disease was defined as an unresectable disease without distant organ metastasis based on resectability status of NCCN guideline in this study. Stag-lap was performed in 67 patients with RD-LA (2007-2012) which were divided into 4 groups according to metastatic site: group CY (peritoneal fluid or washing cytology positive and without any distant organ metastasis); group P (peritoneal dissemination); group L (liver metastasis); group LA (peritoneal fluid or washing cytology negative and without any distant organ metastasis). Clinical backgrounds, survival curves, and prognostic factors were investigated. There were 16 patients in CY group (24%), 13 patients in P group (19%), 10 patients in L group (15%), and 28 patients in LA group (42%). Median survival time was 13 months in CY group and 11 months in LA group, which was significantly better than 7 months in P group, respectively (p<0.05). The rate of emergence of ascites in LA was significantly better than in CY or P groups (p<0.0...Continue Reading

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Citations

Mar 7, 2018·Journal of Surgical Oncology·Victor Hugo Fonseca de JesusFelipe José Fernandez Coimbra
Mar 25, 2019·Journal of Gastrointestinal Cancer·Muslim AtiqRamu G Sudhagoni
Nov 30, 2019·Langenbeck's Archives of Surgery·Atsushi ObaAkio Saiura
Sep 21, 2017·Oncology Letters·Daisuke FurukawaMasato Nakamura
Jan 11, 2017·World Journal of Surgical Oncology·Kohei NishioMasaichi Ohira
Jan 4, 2021·Journal of Cancer Research and Clinical Oncology·Eileen A O'HalloranSanjay S Reddy

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Methods Mentioned

BETA
biopsy
surgical resection
lavage

Software Mentioned

SPSS

Related Concepts

Related Feeds

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.