Abstract
The aim of current study is to verify usefulness of staging laparoscopy (stag-lap) for patient's selection and to find prognostic factors in patients with radiographically defined locally advanced (RD-LA) pancreatic ductal adenocarcinoma (PDAC). The LA disease was defined as an unresectable disease without distant organ metastasis based on resectability status of NCCN guideline in this study. Stag-lap was performed in 67 patients with RD-LA (2007-2012) which were divided into 4 groups according to metastatic site: group CY (peritoneal fluid or washing cytology positive and without any distant organ metastasis); group P (peritoneal dissemination); group L (liver metastasis); group LA (peritoneal fluid or washing cytology negative and without any distant organ metastasis). Clinical backgrounds, survival curves, and prognostic factors were investigated. There were 16 patients in CY group (24%), 13 patients in P group (19%), 10 patients in L group (15%), and 28 patients in LA group (42%). Median survival time was 13 months in CY group and 11 months in LA group, which was significantly better than 7 months in P group, respectively (p<0.05). The rate of emergence of ascites in LA was significantly better than in CY or P groups (p<0.0...Continue Reading
References
Jun 1, 1997·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·H A BurrisD D Von Hoff
Feb 3, 2000·Journal of the National Cancer Institute·P TherasseS G Gwyther
Mar 31, 2004·Lancet·Donghui LiJames L Abbruzzese
Dec 9, 2004·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Margo ShoupKevin C Conlon
Mar 5, 2005·Journal of Hepato-biliary-pancreatic Surgery·Esther H B M TillemanDick J Gouma
Mar 19, 2005·Surgical Endoscopy·R C Liu, L W Traverso
Oct 21, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·D StefanidisC R Thomas
Apr 25, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Malcolm J MooreUNKNOWN National Cancer Institute of Canada Clinical Trials Group
Mar 1, 2008·Journal of the American College of Surgeons·Rebekah WhitePeter Allen
Apr 5, 2008·Surgical Endoscopy·Yumi Hori, UNKNOWN SAGES Guidelines Committee
Feb 28, 2009·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M J M MorakC H J van Eijck
Sep 26, 2009·Journal of Surgical Oncology·Carlo M ContrerasSharon M Weber
May 15, 2010·American Journal of Surgery·Clancy J Clark, L William Traverso
Jan 6, 2011·Pancreas·Sohei SatoiA-Hon Kwon
May 13, 2011·The New England Journal of Medicine·Thierry ConroyUNKNOWN PRODIGE Intergroup
Dec 2, 2011·Annals of Surgical Oncology·K A BickenbachP J Allen
Feb 9, 2012·International Journal of Surgical Oncology·Paul H SugarbakerLana Bijelic
Apr 3, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Hideki UenoMasao Tanaka
May 11, 2013·Journal of Hepato-biliary-pancreatic Sciences·Sohei SatoiTadahiro Takada
Citations
Mar 17, 2017·Journal of Hepato-biliary-pancreatic Sciences·Sohei SatoiMasanori Kon
Oct 30, 2016·Journal of Hepato-biliary-pancreatic Sciences·Ilhan KarabicakMasanori Kon
Mar 7, 2018·Journal of Surgical Oncology·Victor Hugo Fonseca de JesusFelipe José Fernandez Coimbra
Jun 4, 2020·Cancers·Hiroaki YanagimotoMitsugu Sekimoto
Jul 9, 2020·The British Journal of Surgery·S YamadaS Satoi
Nov 9, 2019·BMC Surgery·Sachiyo ShirakawaTakumi Fukumoto
Sep 9, 2020·Surgery Today·Tatsuyuki TakadateMichiaki Unno
Mar 25, 2019·Journal of Gastrointestinal Cancer·Muslim AtiqRamu G Sudhagoni
Sep 3, 2020·Annals of Surgical Oncology·Masaya SuenagaYasuhiro Kodera
Nov 30, 2019·Langenbeck's Archives of Surgery·Atsushi ObaAkio Saiura
Jan 7, 2017·Annals of Surgery·Sohei SatoiMasanori Kon
Sep 21, 2017·Oncology Letters·Daisuke FurukawaMasato Nakamura
Jan 11, 2017·World Journal of Surgical Oncology·Kohei NishioMasaichi Ohira
Jan 4, 2021·Journal of Cancer Research and Clinical Oncology·Eileen A O'HalloranSanjay S Reddy
Mar 13, 2021·The British Journal of Surgery·A ObaY Takahashi
Apr 17, 2021·Annals of Gastroenterological Surgery·Hiroyuki KatoSatoshi Arakawa
May 23, 2021·Journal of Hepato-biliary-pancreatic Sciences·Tatsuo HataMichiaki Unno
Jul 28, 2021·Journal of Hepato-biliary-pancreatic Sciences·Tatsuma SakaguchiMitsugu Sekimoto
Aug 17, 2021·Journal of Gastroenterology and Hepatology·Tomoya EmoriMasayuki Kitano