PMID: 9443697Jan 27, 1998Paper

A clinical trial of hypertonic saline nasal spray in subjects with the common cold or rhinosinusitis

Archives of Family Medicine
P AdamR L Blake

Abstract

To determine whether hypertonic saline nasal spray relieves nasal symptoms and shortens illness duration in patients with the common cold or acute rhinosinusitis. Randomized trial with 2 control groups. Two family practice clinics. One hundred forty-three adult patients with a cold or sinus infection. Patients with allergic rhinitis, symptoms for more than 3 weeks, or other respiratory diagnoses were excluded, as were those who had used topical decongestants. Hypertonic saline or normal saline spray 3 times a day or observation. Subjects completed a 7-day symptom checklist that included a well-being question ("Do you feel back to normal?"). Nasal symptom score (sum of scores for nasal congestion, rhinorrhea, and headache) on day 3 and day of well-being (day of symptom resolution). Data were collected for 119 subjects. No difference was found in either primary outcome when hypertonic saline was compared with either normal saline or observation. Mean day of well-being was 8.3 (95% confidence interval [CI], 6.9-9.7), 9.2 (95% CI, 6.9-11.43), and 8.0 (95% CI, 6.7-9.3) days in the hypertonic saline, normal saline, and observation groups, respectively. Day 3 mean nasal symptom score was 3.8 (95% CI, 3.0-4.5) for hypertonic saline, 3....Continue Reading

Citations

Sep 7, 2007·HNO·B A StuckUNKNOWN German Society for Otorhinolaryngology, Head and Neck Surgery
Dec 6, 2011·HNO·B A StuckUNKNOWN German Society of Otorhinolaryngology, Head and Neck Surgery
Jan 29, 2013·Current Allergy and Asthma Reports·Nils Achilles, Ralph Mösges
Sep 28, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Richard M RosenfeldDavid L Witsell
Oct 31, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Garrett Hauptman, Matthew W Ryan
Jul 13, 2000·The Laryngoscope·L T TomookaT M Davidson
Feb 12, 2011·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Martin DesrosiersIan J Witterick
Apr 15, 2014·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·F AlauzetL Giovannini-Chami
Feb 20, 2016·International Forum of Allergy & Rhinology·Richard R OrlandiDavid W Kennedy
Jan 21, 2014·Primary Care·Alexi DeCastroWilliam J Hueston
Jun 26, 2012·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Reena Khianey, John Oppenheimer
Apr 15, 2011·Mayo Clinic Proceedings·Eli O Meltzer, Daniel L Hamilos
Jan 31, 2006·Immunology and Allergy Clinics of North America·Gary A Incaudo, Patricia Takach
Dec 7, 2010·Journal of Applied Toxicology : JAT·Joke LenoirJean-Paul Remon
Jan 3, 2015·Brazilian Journal of Otorhinolaryngology·Wilma T Anselmo-LimaShirley Shizue Nagata Pignatari
Jul 13, 2013·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Joke LenoirEls Adriaens
Feb 24, 2015·Brazilian Journal of Otorhinolaryngology·Wilma T Anselmo-LimaShirley Shizue Nagata Pignatari
Nov 18, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Myeong Sang YuDae Jun Lim
Jan 18, 2017·MMW Fortschritte der Medizin·Nina Dippold, Ludger Klimek
Apr 4, 2015·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Richard M RosenfeldMaureen D Corrigan
May 12, 2017·International Journal of Environmental Research and Public Health·Nicola Principi, Susanna Esposito
Jul 18, 2001·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·D G HeatleyG E Leverson
Oct 28, 2014·The Cochrane Database of Systematic Reviews·Nader Shaikh, Ellen R Wald
Jun 30, 2011·American Journal of Rhinology & Allergy·Myeong Sang YuYong Ju Jang
May 19, 2018·American Journal of Rhinology & Allergy·Dichapong KanjanawaseeKornkiat Snidvongs
Mar 26, 2003·European Journal of Pediatrics·Christoph GrüberMalte Bühring
Apr 22, 2015·The Cochrane Database of Systematic Reviews·David KingGeoffrey K P Spurling
Nov 26, 2019·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Lakshana Deve, Jayita Poduval
Apr 26, 2016·The Cochrane Database of Systematic Reviews·Richard J HarveyGlenis Scadding
Apr 22, 2008·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Cássio da Cunha IbiapinaAlvaro Augusto Souza da Cruz Filho
May 6, 2020·Lung India : Official Organ of Indian Chest Society·Sheetu SinghVirendra Singh
Jun 12, 2017·Current Allergy and Asthma Reports·Kornkiat Snidvongs, Sanguansak Thanaviratananich
Jan 15, 2021·Scientific Reports·Sze Lei PangFook Tim Chew
Dec 29, 2020·Laryngoscope Investigative Otolaryngology·Patorn PiromchaiTriphoom Suwanwech
Nov 26, 2020·International Forum of Allergy & Rhinology·Richard R OrlandiBing Zhou
May 8, 2021·International Forum of Allergy & Rhinology·Wirach ChitsuthipakornKornkiat Snidvongs
Jul 1, 2021·QRB Discovery·David EdwardsRobert Langer

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