PMID: 1026543Jan 1, 1976

A clinical trial of temazepam, a sleep inducer, in hospital patients

The Journal of International Medical Research
A PinesJ F Rooney


Temazepam, a common metabolite of diazepam and oxazepam, was evaluated as a sleep inducer. A dose of 20 mg, in a Scherer capsule formulation, was compared with 200 mg of amylobarbitone sodium in a between-patients, randomized study. Patient and staff assessments were used. No statistically significant difference as to onset of sleep, duration or quality of sleep or morning drowsiness was found using the patients' assessments. The staff recorded significantly less daytime dozing and morning hangover in patients receiving temazepam. Side-effects were mild and confined mainly to drowsiness on awakening. Two patients, both on amylobarbitone sodium, withdrew from the study because of increasing confusion.


Sep 1, 1966·The British Journal of Psychiatry : the Journal of Mental Science·S Crown, A H Crisp


Nov 26, 2013·The Cochrane Database of Systematic Reviews·Allison Hirst, Richard Sloan
Jan 1, 1979·The Journal of International Medical Research·H S Sussman
Jul 1, 1981·Pharmacotherapy·M M Mitler
Sep 1, 1982·Drug Intelligence & Clinical Pharmacy·J C McElnayB Alexander
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