PMID: 2117424Jul 1, 1990Paper

A clinical trial of two parenteral nutrition solutions in neonates

Archives of Disease in Childhood
N McIntosh, V Mitchell

Abstract

Sixty eight neonates requiring total or supplemental parenteral nutrition in the first week of life were randomly allocated either Vamin 9 glucose (n = 34) or MB233G (n = 34) in a double blind trial. Twenty infants were withdrawn: four because they died before 5 days of age and 16 because the amino acids were required for less than the five days of the trial. The solutions were isocaloric (1.6 MJ/l, 380 kcal/l) and with the same nitrogen content (2.79 g/l) and were infused at rates and volumes determined by clinical staff on the basis on the infants, clinical condition and serum electrolyte biochemistry. There was an excess of deaths in the group treated with Vamin 9 glucose particularly related to babies weighing greater than or equal to 1000 g. Infants less than 1000 g receiving the Vamin 9 glucose preparation required amino acids for twice as long. There was no significant difference between the weight losses or head circumference during the study period. Plasma aminograms in the group receiving Vamin 9 glucose showed concentrations of phenylalanine, tyrosine, proline, serine, and aspartic acid to be significantly higher than the reference range. Multiple regression analysis suggested that phenylalanine was the primary abnor...Continue Reading

References

Apr 1, 1978·The Journal of Pediatrics·F Pohlandt
Nov 8, 1986·Lancet·J W PuntisP A Ball
Dec 24, 1988·Lancet·S G MittonM J Brueton
Feb 1, 1974·The Journal of Pediatrics·H P MartinH P Chase
Sep 26, 1970·British Medical Journal·F CockburnJ O Forfar
Jan 1, 1984·Biology of the Neonate·N McIntoshR Heath
Jul 1, 1981·The Journal of Pediatrics·W L Miller
Jan 1, 1984·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·J A SturmanM D Neuringer

❮ Previous
Next ❯

Citations

Jan 1, 1992·Nutrition Research Reviews·J B Morgan, I Z Kovar
Oct 8, 1999·Journal of Pediatric Gastroenterology and Nutrition·N T van HeekA Vos
Nov 1, 1995·British Journal of Obstetrics and Gynaecology·D C Wilson
Apr 1, 1991·Archives of Disease in Childhood·J W Puntis, I W Booth
Mar 1, 1993·Archives of Disease in Childhood·A Lucas, O E Pratt
May 1, 1993·Archives of Disease in Childhood·A LucasR M Morley
Nov 2, 2014·Pediatric Research·Shiraz BadurdeenJames A Berkley
Mar 6, 2018·The Cochrane Database of Systematic Reviews·David A OsbornSrinivas Bolisetty
Aug 3, 2006·Acta Paediatrica·Frank Pohlandt
Oct 23, 2020·Archives of Disease in Childhood·Rachel Pybus, John W Puntis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.