A clinicopathological study of resected adenocarcinoma 2 cm or less in diameter

The Annals of Thoracic Surgery
Norihiko IkedaShinya Okada

Abstract

The biological behavior of small adenocarcinoma is different in each patient and these are especially enormous differences when evaluating solid tumors and nonsolid tumors. A total of 159 adenocarcinomas 2 cm or less in diameter were studied. Several clinicopathological factors were retrospectively analyzed. The diameter of the primary tumors was less than 1 cm in 47 patients, 1-1.5 cm in 49 patients, and 1.5-2 cm in 63 patients, respectively. Almost all patients (147) were pathologic N0 and there were 12 node-positive patients (7.5%). Lymph-node involvement was observed in 1 patient with a tumor diameter measuring less than 1 cm and in 11 patients with a tumor diameter measuring 1-2 cm. According to Noguchi' s classification, 33 patients belonged to class A or B, 71 patients belonged to class C, and 55 patients belonged to class D, E, or F. The ratio of ground-glass opacity (GGO) area in the main tumor in high resolution computed tomography was classified into two groups with a threshold of 50%. There were 44 patients with a GGO ratio of equal to or greater than 50%, none of which indicated lymph-node metastasis or tumor recurrence during follow-up (5-year survival = 100%). On the contrary among 115 patients with a GGO ratio l...Continue Reading

References

Aug 1, 1980·The American Journal of Surgical Pathology·Y ShimosatoT Kameya
Dec 19, 1998·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·C KonakaH Kato
Jan 5, 2000·The Annals of Thoracic Surgery·M HigashiyamaK Kuriyama
Apr 6, 2000·The Annals of Thoracic Surgery·K SuzukiY Nishiwaki
Sep 2, 2000·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·A López-EncuentraC Wittekind
Jul 19, 2001·The British Journal of Radiology·J R Ellis, F V Gleeson
Feb 15, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Tomotaka SobueKenji Eguchi
Apr 17, 2002·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Shodayu TakashimaShusuke Sone
Aug 7, 2003·The Annals of Thoracic Surgery·Daizo KondoShoji Hoshi
Sep 2, 2003·Journal of Surgical Oncology·Elizabeth E Warner, James L Mulshine

❮ Previous
Next ❯

Citations

Feb 25, 2010·Surgery Today·Takayuki Fukui, Tetsuya Mitsudomi
May 7, 2005·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·Arthur E Baue
Feb 9, 2010·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Masayoshi InoueMeinoshin Okumura
Jan 21, 2012·The Korean Journal of Thoracic and Cardiovascular Surgery·Jeong Su ChoChoon Taek Lee
Nov 30, 2011·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Chia-Hung LuPan-Chyr Yang
Jun 5, 2007·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Takayuki FukuiTetsuya Mitsudomi
Jun 23, 2009·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Yoichi AnamiMasayuki Noguchi
Nov 26, 2013·Radiologic Clinics of North America·Roy A RaadJane P Ko
Nov 8, 2011·Clinics in Chest Medicine·Frank C Detterbeck, Robert J Homer
Aug 10, 2005·Seminars in Thoracic and Cardiovascular Surgery·Nasser K AltorkiClaudia I Henschke
Nov 28, 2015·Journal of Cancer Research and Therapeutics·Yi-Feng ZhengZhi-Qiang Han
Apr 1, 2015·The Annals of Thoracic Surgery·Hiroyuki SakuraiHisao Asamura
May 27, 2016·Interactive Cardiovascular and Thoracic Surgery·Yuki MatsumuraUNKNOWN Japanese Association for Chest Surgery
Oct 13, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Valerie W Rusch
Aug 25, 2017·European Radiology·Rowena YipClaudia I Henschke
Apr 11, 2018·Current Opinion in Pulmonary Medicine·Varvara Mironova, Justin D Blasberg
May 15, 2013·Journal of Neurosurgery·Michael G HartRamez W Kirollos
Aug 4, 2010·Neurosurgery·Morgan BroggiCharles Teo
Nov 24, 2011·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·T BabaF Tanaka
Sep 28, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Yuya IshikawaToru Bando
Oct 16, 2019·The Journal of Thoracic and Cardiovascular Surgery·Ethan PaniSunil Singhal
Dec 28, 2005·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Katsuhiko ShimizuHarubumi Kato

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.