A cluster of Pneumocystis infections among renal transplant recipients: molecular evidence of colonized patients as potential infectious sources of Pneumocystis jirovecii

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Solène Le GalGilles Nevez

Abstract

Eighteen renal transplant recipients (RTRs) developed Pneumocystis jirovecii infections at the renal transplantation unit of Brest University Hospital (Brest, Brittany, France) from May 2008 through April 2010, whereas no cases of P. jirovecii infection had been diagnosed in this unit since 2002. This outbreak was investigated by identifying P. jirovecii types and analyzing patient encounters. The identification of P. jirovecii internal transcribed spacer (ITS) types was performed on P. jirovecii isolates from the 18 RTRs (12 patients with Pneumocystis pneumonia [PCP], 6 colonized patients), 22 unlinked control patients (18 patients with PCP, 4 colonized patients), and 69 patients (34 patients with PCP, 35 colonized patients) with contemporaneously diagnosed P. jirovecii infections in the Brest geographic area. A transmission map was drawn up. Its analysis was combined with the results of P. jirovecii typing. P. jirovecii ITS type identification was successful in 14 of 18 RTRs, 15 of 22 control patients, and 48 of the 69 patients. Type Eg was the most frequent type in the 3 patient groups. However, its frequency was significantly higher in the first patient group than in the 2 other groups (P < .05 and P < .01, respectively). F...Continue Reading

References

Feb 1, 1992·The Journal of Pathology·S E PetersJ M Hopkin
Mar 1, 1983·The Journal of Infectious Diseases·W T HughesB M Smith
Dec 1, 1993·Infection and Immunity·W ChenA G Harmsen
Feb 1, 1997·The Journal of Infectious Diseases·B R LaneS R Meshnick
Aug 15, 1998·Journal of Clinical Microbiology·X TangC H Lee
Mar 4, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·S M GordonD L Longworth
Nov 1, 2000·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A DumoulinE Dei-Cas
Aug 27, 2002·Emerging Infectious Diseases·James R StringerAnn E Wakefield
Nov 26, 2003·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Olga MatosFrancisco Antunes
Apr 9, 2004·Journal of Clinical Microbiology·Frans J L RobbertsLynda J Chalkley
Oct 27, 2004·Emerging Infectious Diseases·Laurence HuangJannik Helweg-Larsen
Oct 27, 2004·Emerging Infectious Diseases·Charles Ben BeardBettina Lundgren
Mar 9, 2005·Emerging Infectious Diseases·Britta HöckerPhilippe M Hauser
May 6, 2005·Journal of Clinical Microbiology·Suradej SiripattanapipongPeerapan Tan-ariya
Apr 5, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mark G J de BoerJan P Vandenbroucke
Dec 11, 2007·American Journal of Infection Control·Jane D SiegelUNKNOWN Health Care Infection Control Practices Advisory Committee
Sep 26, 2008·Parasite : Journal De La Société Française De Parasitologie·G NevezA Totet
Sep 12, 2009·Transplant Infectious Disease : an Official Journal of the Transplantation Society·S GianellaN J Mueller
Jan 28, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·U AllenR Miller
Jun 25, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Firas ChoukriAnne Totet
Mar 10, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Geertrude H StruijkFrederike J Bemelman

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Citations

Jun 25, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Brian J NankivellWieland Meyer
Sep 25, 2014·Indian Journal of Nephrology·A JairamA K Hooda
Jun 7, 2013·Kidney International·Jeremy R ChapmanPeter S MacDonald
Apr 3, 2016·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M DepypereK Lagrou
Jul 17, 2015·Open Forum Infectious Diseases·Jonathan J JulianoLaurence Huang
Jun 25, 2015·BioMed Research International·Laura Elena Carreto-BinaghiMaria Lucia Taylor
Jun 3, 2016·Frontiers in Microbiology·Alexandre AlanioStéphane Bretagne
Aug 24, 2016·The Journal of Antimicrobial Chemotherapy·Alexandre AlanioUNKNOWN 5th European Conference on Infections in Leukemia (ECIL-5), a joint venture of The European Group for Blood and Marrow Trans
Sep 30, 2016·Infectious Diseases·Carlos FritzscheEmil C Reisinger
Nov 29, 2016·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Claire WintenbergerOlivier Epaulard
Feb 9, 2017·The Journal of Hospital Infection·T InksterA M Bal
Mar 8, 2018·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Giacomo VeroneseMaria Frigerio
Nov 27, 2015·Clinical Medicine Insights. Circulatory, Respiratory and Pulmonary Medicine·Norihiko GotoYoshihiko Watarai
Jun 14, 2018·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Romain Miguel MontanesFrançois Durand
Jul 11, 2014·Journal of Clinical Microbiology·Florence Robert-GangneuxJean-Pierre Gangneux
May 12, 2017·Clinical Microbiology Reviews·Alexandre AlanioStéphane Bretagne
Sep 5, 2013·The Journal of Eukaryotic Microbiology·Peter D Walzer
Jan 25, 2014·Transplant Infectious Disease : an Official Journal of the Transplantation Society·L Perez-OrdoñoC Cervera
Oct 22, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·UNKNOWN Anofel Association
May 27, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·William VindriosJean-Christophe Lucet
Nov 30, 2019·Mycopathologia·Sarah DellièreAlexandre Alanio
Mar 12, 2020·MBio·Ousmane H CisséJoseph A Kovacs
Mar 21, 2013·Nephrology·Carlos FritzscheEmil C Reisinger
Sep 28, 2015·Journal of Fungi·Xavier IriartAntoine Berry
May 12, 2019·Clinical Transplantation·Jay A FishmanUNKNOWN AST Infectious Diseases Community of Practice
Aug 24, 2019·Emerging Infectious Diseases·Guillaume DesoubeauxPhilippe Poirier
Feb 16, 2013·Current Opinion in Pulmonary Medicine·Gemma E Hayes, David W Denning
Mar 14, 2017·Future Microbiology·Wolfram WindischOliver Schildgen

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