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A codon model of nucleotide substitution with selection on synonymous codon usage

bioRxiv

Aug 12, 2014

Laura Salter KubatkoMichael A. Gilchrist

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Abstract

The quality of phylogenetic inference made from protein-coding genes depends, in part, on the realism with which the codon substitution process is modeled. Here we propose a new mechanistic model that combines the standard M0 substitution model of Yang (1997) with a simplified model fro...read more

Mentioned in this Paper

Mutation Abnormality
Codon (Nucleotide Sequence)
Saccharomyces cerevisiae
Gilchrist Disease
Nucleotides
Codon Genus
6
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  • A codon model of nucleotide substitution with selection on synonymous codon usage

    bioRxiv

    Aug 12, 2014

    Laura Salter KubatkoMichael A. Gilchrist

    PMID: 990007849

    DOI: 10.1101/007849

    Abstract

    The quality of phylogenetic inference made from protein-coding genes depends, in part, on the realism with which the codon substitution process is modeled. Here we propose a new mechanistic model that combines the standard M0 substitution model of Yang (1997) with a simplified model fro...read more

    Mentioned in this Paper

    Mutation Abnormality
    Codon (Nucleotide Sequence)
    Saccharomyces cerevisiae
    Gilchrist Disease
    Nucleotides
    6

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