A cohort investigation of anaemia, treatment and the use of allogeneic blood transfusion in colorectal cancer surgery

Annals of Medicine and Surgery
Barrie D KeelerA G Acheson

Abstract

Preoperative identification and treatment of anaemia is advocated as part of Patient Blood Management due to the association of adverse outcome with the perioperative use of blood transfusion. This study aimed to establish the rate of anaemia identification, treatment and implications of this preoperative anaemia on ARBT use. All patients who underwent elective surgery for colorectal cancer over 18 months at a single Tertiary Centre were reviewed. Electronic databases and patient casenotes were reviewed to yield required data. Complete data was available on 201 patients. 67% (n = 135) had haemoglobin tested at presentation. There was an inverse correlation between tumour size and initial haemoglobin (P < 0.01, Rs = -0.3). Initial haemoglobin levels were significantly lower in patients with right colonic tumours (P < 0.01). Patients who were anaemic preoperatively received a mean 0.91 units (95%CI 0-0.7) per patient which was significantly higher than non-anaemic patients (0.3 units [95%CI 0-1.3], P < 0.01). For every 1 g/dl preoperative haemoglobin increase, the likelihood of transfusion was reduced by approximately 40% (OR 0.57 [95%CI 0.458-0.708], P < 0.01). Laparoscopic surgery was associated with fewer anaemic patients tran...Continue Reading

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Citations

Sep 25, 2017·Transfusion Medicine·A Butcher, T Richards
Mar 16, 2018·Annals of the Royal College of Surgeons of England·S MashlabUNKNOWN Nottingham Colorectal Service
Jun 2, 2018·Gastroenterology Research and Practice·Liu LiuQiang Huang
Feb 13, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Qinghua ShaoGuangxia Ni
Dec 1, 2020·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Magnus PlougTorben Knudsen

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