A cohort study of incident myopia in Singaporean children

Investigative Ophthalmology & Visual Science
Seang-Mei SawTien-Yin Wong

Abstract

To determine the risk factors of incident myopia in a school-based cohort study in Singaporean children. A 3-year prospective cohort study was conducted in Singaporean school children aged 7 to 9 years in three schools at entry. Chinese children without myopia at baseline (n = 994) were included in the analysis. The main outcome was incident myopia, defined as spherical equivalent (SE) at least -0.75 D based on cycloplegic autorefraction. Other definitions of incident myopia, at least -0.5 D and at least -1.0 D, were also assessed. After controlling for school, age, gender, income, reading in books per week and intelligence quotient (IQ) test scores, we found the relative risk (RR) of incident myopia defined as -0.75 D to be 1.55 (95% confidence interval [CI] 1.18-2.04) for two versus no myopic parents. The multivariate RR of myopia for IQ in the third versus first tertile was 1.50 (95% CI, 1.19-1.89). However, the RR of incident myopia was 1.01 (95% CI, 0.97-1.05) for every unit increase in books read per week. Similar results were obtained with definitions of -0.5 and -1.0 D for incident myopia. These data provide new prospective evidence of essential links between parental myopia, IQ scores and subsequent myopia development....Continue Reading

Citations

Mar 7, 2013·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·A Landmann, E Bechrakis
Jun 22, 2012·Journal of Biosocial Science·Gail PachecoSusan Morton
Jan 22, 2009·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Donald O Mutti, Karla Zadnik
Dec 21, 2010·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Laura A WilliamsDonald O Mutti
Jan 25, 2011·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Donald O Mutti, Amanda R Marks
Mar 30, 2013·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Zhong LinYuan Bo Liang
Mar 18, 2011·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·W Neil Charman
Dec 14, 2011·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Carly Siu-Yin LamLily Yee-Lai Chan
Mar 19, 2014·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Zhong LinYuan Bo Liang
Sep 18, 2013·International Ophthalmology·Andrea RussoCiro Costagliola
Jul 3, 2015·Experimental and Therapeutic Medicine·Xiaoyu ZhangXingtao Zhou
Oct 27, 2015·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Dharani RamamurthySeang-Mei Saw
Jul 9, 2010·American Journal of Ophthalmology·Shu E Soh, Seang Mei Saw
Feb 4, 2010·Ophthalmology·Chiea C KhorSeang-Mei Saw
Jan 19, 2010·Ophthalmology·Laurence S LimSeang-Mei Saw
Sep 13, 2012·Journal of Pediatric Ophthalmology and Strabismus·Ihsan CacaYilmaz Palanci
Feb 20, 2007·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Yvonne Ling
May 15, 2013·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Zhong LinKenneth J Ciuffreda
Sep 13, 2011·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Beau B BruceDavid W Wright
Dec 16, 2010·Clinical Genetics·R Wojciechowski
Feb 23, 2010·American Journal of Ophthalmology·Noha S EkdawiBrian G Mohney
Oct 22, 2013·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Muhammad Salman HaleemBaihua Li
May 7, 2013·Experimental Eye Research·Amanda N FrenchKathryn A Rose
Apr 29, 2015·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Wen-Juan HuaFang-Biao Tao
May 12, 2015·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Laurence Shen LimSeang-Mei Saw
Aug 12, 2014·The Journal of Allergy and Clinical Immunology·Anand Kumar AndiappanFook Tim Chew
Oct 29, 2013·Ophthalmic Epidemiology·Shi-Ming LiUNKNOWN Anyang Childhood Eye Study Group
Feb 6, 2015·Journal of Ophthalmology·Ajai Verma, Abhishek Verma
Aug 9, 2011·Ophthalmology·Chameen SamarawickramaSeang-Mei Saw
Apr 26, 2014·Frontiers in Neuroanatomy·Emiliano BrunerNaomichi Ogihara
Oct 27, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Zhong LinYuan Bo Liang
Nov 7, 2016·Environmental Research·Payam DadvandMark J Nieuwenhuijsen
Sep 6, 2018·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Neema Ghorbani MojarradJeremy A Guggenheim

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