A cohort study of women with a Fontan circulation undergoing preconception counselling

Heart
Matthew CauldwellMark R Johnson

Abstract

To describe outcomes for women with a Fontan circulation attending preconception counselling (PCC). Exploring (1) impact of counselling on decision to become pregnant; (2) pregnancy rates in those opting for pregnancy and (3) short-term and long-term outcome of those who succeeded in becoming pregnant. Retrospective review of women aged 16-45 years with a Fontan circulation from 1994 to 2014. 58 women were offered PCC, 3 declined and 55 received PCC. Following PCC, 15 opted against conception, 16 decided to delay pregnancy, 19 attempted pregnancy and 5 were lost to follow-up. Of the 19 women, 14 succeeded, becoming pregnant a total of 43 times (median 1, range 1-9). Of these, 6 miscarried all pregnancies. 8 carried 14 pregnancies to viability. Baseline hypoxaemia and cardiac disease in pregnancy (CARPREG) score was similar in those opting for and against pregnancy, but CARPREG score was better in those delaying conception. Women exclusively miscarrying or unable to conceive were more likely to have baseline hypoxaemia and greater CARPREG score. Cardiac complications included arrhythmia requiring treatment (n = 4) and one thromboembolism. Obstetric complications were greater in women with a Fontan circulation, 10 preterm births ...Continue Reading

References

Jul 15, 1990·The American Journal of Cardiology·M M CanobbioB L George
Sep 1, 1996·Journal of the American College of Cardiology·M M CanobbioB J Koos
Oct 8, 1999·The American Journal of Cardiology·J TherrienJ Somerville
Jun 23, 2000·BMJ : British Medical Journal·A M Nybo AndersenM Melbye
Jan 15, 2002·The Australian & New Zealand Journal of Obstetrics & Gynaecology·J V Hoare, D Radford
Feb 2, 2006·Heart·W DrenthenUNKNOWN ZAHARA Investigators
Feb 2, 2006·Circulation·Paul KhairyMichael J Landzberg
Sep 16, 2006·Heart·Sara ThorneCatherine Nelson-Piercy
Jul 28, 2010·International Journal of Cardiology·Nicole JastrowLine Leduc
Sep 4, 2010·Journal of the American College of Cardiology·Elizabeth A StephensonUNKNOWN Pediatric Heart Network Investigators
Jan 5, 2011·International Journal of Cardiology·Georgios GiannakoulasTom Wong
Mar 23, 2011·Obstetrics and Gynecology·Emily GelsonMark Johnson
Nov 23, 2011·Expert Review of Cardiovascular Therapy·Laurianne Le GloanPaul Khairy
Jun 8, 2012·The Journal of Obstetrics and Gynaecology Research·Seiji InoueYuji Hiramatsu
Jan 22, 2013·International Journal of Cardiology·L IdornL Søndergaard
Feb 15, 2014·World Journal of Cardiology·Olli Arjamaa
Apr 2, 2015·International Journal of Cardiology·Marielle GoutonMagalie Ladouceur

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Citations

May 31, 2016·International Journal of Cardiology·Matthew CauldwellMark R Johnson
Oct 12, 2016·International Journal of Obstetric Anesthesia·R S MonteiroM A Gatzoulis
Feb 23, 2018·BJOG : an International Journal of Obstetrics and Gynaecology·M Cauldwell, C Nelson-Piercy
Oct 22, 2018·Congenital Heart Disease·Georges EphremFred Rodriguez
Dec 3, 2016·European Respiratory Review : an Official Journal of the European Respiratory Society·Paul Clift, David Celermajer
Jul 2, 2019·Circulation·Jack RychikUNKNOWN American Heart Association Council on Cardiovascular Disease in the Young and Council on Cardiovascular and Stroke Nursing
Aug 24, 2017·Cardiology in Review·Despina NtiloudiHaralambos Karvounis
May 13, 2018·Circulation. Cardiovascular Quality and Outcomes·Alvaro Garcia RoperoGruschen R Veldtman
Apr 11, 2018·Obstetric Medicine·Emily MoroneyDominica Zentner
Oct 12, 2020·Journal of Assisted Reproduction and Genetics·Yuli Y KimClarisa R Gracia
Nov 26, 2020·Heart·Andrea GirniusGruschen R Veldtman
Jun 14, 2021·Journal of Gynecology Obstetrics and Human Reproduction·Sébastien GrandfilsPatrick Emonts

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