A Cohort Study to Examine the Use of Chinese Herbal Medicine in Combination With Conventional Therapies for Patients With Hepatocellular Carcinoma in China

Integrative Cancer Therapies
Lingling SunLizhu Lin

Abstract

Hepatocellular carcinoma (HCC) is one of the major malignancies associated with high mortality rates. Chinese herbal medicine (CHM) alone, or in combination with conventional therapies (CT), has been widely used for patients with HCC in China. This study aims to explore how integrative therapy (IT) through the combination of CHM and CT affects the survival of patients with intermediate-advanced HCC. A retrospective cohort study was performed at the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China. Data of consecutive patients diagnosed with intermediate-advanced HCC and a specific traditional Chinese medicine diagnostic pattern between January 2006 and December 2013 were retrieved from the electronic medical record system at the hospital. Patients were divided into 3 groups based on the therapies used, that is, IT, CHM alone, and CT alone, and the survival times of these patients was compared. A total of 328 patients were included in this study. Median follow-up period was 26.4 months (95% confidence interval [CI] = 22.7-38.9). Median overall survival was 11.0 months for IT, 8.6 months for CHM, and 9.4 months for CT groups ( P < .001). The adjusted hazard ratio (HR) of death for the IT gro...Continue Reading

References

Aug 1, 1996·Controlled Clinical Trials·M Schemper, T L Smith
Jan 6, 1999·Controlled Clinical Trials·W D Dupont, W D Plummer
Feb 24, 2001·Journal of Gastroenterology and Hepatology·I MericanD Z Xu
Jan 24, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Josep M Llovet, Jordi Bruix
Jul 25, 2008·The New England Journal of Medicine·Josep M LlovetUNKNOWN SHARP Investigators Study Group
Mar 11, 2010·Liver International : Official Journal of the International Association for the Study of the Liver·Edoardo G GianniniUNKNOWN Italian Liver Cancer group
Feb 23, 2012·Lancet·Alejandro FornerJordi Bruix
May 9, 2012·Phytotherapy Research : PTR·Jian-Qing YuJia-Chuan Lei
Oct 25, 2012·Evidence-based Complementary and Alternative Medicine : ECAM·Jennifer L McQuadeLorenzo Cohen
Aug 2, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Chong ZhongRong-Ping Guo
Sep 16, 2014·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayFreddie Bray
Feb 6, 2015·CA: a Cancer Journal for Clinicians·Lindsey A TorreAhmedin Jemal
Apr 16, 2015·Liver International : Official Journal of the International Association for the Study of the Liver·Yueh-Hsiang LiaoTsai-Chung Li

❮ Previous
Next ❯

Software Mentioned

Empower R
Statistical Package for Social Sciences ( SPSS )

Related Concepts

Related Feeds

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.