A Color Segmentation-Based Method to Quantify Atherosclerotic Lesion Compositions with Immunostaining

Methods in Molecular Biology
Congqing WuHong Lu

Abstract

There is an increasing recognition that atherosclerotic lesion composition, rather than size, is the determinant of acute events. Immunostaining is a commonly used method to characterize atherosclerotic lesion compositions. Here, we describe a color segmentation-based approach in HSI (hue, saturation, and intensity) color mode, which minimizes subjectivity and produces accurate and consistent quantifications of atherosclerotic lesion compositions.

Citations

Jul 22, 2017·Arteriosclerosis, Thrombosis, and Vascular Biology·Alan DaughertyUNKNOWN American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology; and Council on Basic Cardiovascular
Jul 22, 2017·Circulation Research·Alan DaughertyUNKNOWN American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology; and Council on Basic Cardiovascular

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

© 2022 Meta ULC. All rights reserved