A colorimetric sensing platform for azodicarbonamide detection in flour based on MnO2 nanosheets oxidative system.

Analytical and Bioanalytical Chemistry
Luwei ZhangCuiping Yao

Abstract

Azodicarbonamide (ADA), as a dough conditioner food additive in flour, can be turned into toxic biurea and semicarbazide after high temperature processing. Hence, the using of ADA in food material should be strictly controlled, and the detection of ADA is very important for consumers' safety and health. Herein, a simple and fast colorimetric strategy has been developed for ADA detection based on the MnO2 nanosheets-3,3',5,5'-tetramethylbenzidine (TMB)-glutathione (GSH) as oxidative sensing system (MnO2-TMB-GSH). Since the ADA can selectively react with GSH via oxidizing the sulfydryl (-SH) group of GSH to disulfide bond (S-S), which makes GSH unable to reduce MnO2 nanosheets and restore its oxidase-like activity. The absorbance changes of the TMB solution depended on ADA content. The MnO2-TMB-GSH colorimetric platform can detect the ADA with a linear range of 10 μmol L-1 (11.6 ppm) to 400 μmol L-1 (464 ppm), and the limit of detection (LOD) is 3.3 μmol L-1 (3.51 ppm). Some potential interferences in real sample were tested and did not affect the MnO2-TMB-GSH colorimetric platform for ADA detection. Furthermore, the sensing platform was applied for detecting ADA in real flour sample with a recovery of 96%-105% (RSD < 5%). This c...Continue Reading

References

Jun 11, 2005·Analytical and Bioanalytical Chemistry·Maria Beatriz de la Calle, Elke Anklam
Feb 29, 2008·Journal of Agricultural and Food Chemistry·Gregory O NoonanGregory W Diachenko
Oct 13, 2009·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Dimitris VlastosKlimentini Epeoglou
Feb 14, 2012·Biosensors & Bioelectronics·Yi WanYi Wang
Jun 4, 2013·Chemical Communications : Chem Comm·Zhiyuan FangLingwen Zeng
Apr 8, 2020·Nanoscale Horizons : the Home for Rapid Reports of Exceptional Significance in Nanoscience and Nanotechnolgy·Juan ChenYuehe Lin

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