PMID: 9633890Jun 20, 1998Paper

A common polymorphism in the tumour necrosis factor-alpha gene associated with high TNF levels is not a risk factor for venous thromboembolism

British Journal of Haematology
K BrownT Baglin

Abstract

The odds ratio of homozygosity or heterozygosity for the TNF2 polymorphism in 575 patients with venous thromboembolism compared to controls was found to be 1.0 (95% CI 0.4-2.1) and 1.1 (95% CI 0.8-1.4) respectively. Comparing subgroups of patients and controls with the factor V Leiden mutation the odds ratio for the TNF2 polymorphism was 0.7 (95% CI 0.2-2.2). Despite evidence of a link between high tumour necrosis factor (TNF) levels and hypercoagulability, our results do not indicate a link between the genetic regulation of TNF production and venous thromboembolic disease.

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Citations

Jul 16, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M RoselliF Guadagni
Dec 17, 2009·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Hunkar BatikhanMuharrem Gerceker
Mar 1, 2005·Thrombosis Research·Zeynep Ceren KarahanNejat Akar
Nov 23, 2006·Thrombosis Research·Fabiano PieroniRendrik F Franco
Oct 2, 2007·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Steven M Greenberg
Jan 31, 2006·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Tansu SipahiNejat Akar
Sep 26, 2003·The Proceedings of the Nutrition Society·Valerie A Holmes
Nov 5, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Ken-Pen WengLuo-Ping Ger
Mar 1, 2012·American Journal of Hematology·John A Heit
Apr 3, 2015·The Journal of Nutrition·Daniel J RaitenUNKNOWN INSPIRE Consultative Group
Jan 7, 2018·Acta orthopaedica et traumatologica turcica·Bülent ErdemliDerya Biriken
May 24, 2003·Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis·Nejat AkarNilgün Cakar
Apr 9, 2005·Journal of Pediatric Endocrinology & Metabolism : JPEM·Zehra AycanAysun Bideci

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