A common structure for the potexviruses

Virology
Amy KendallGerald Stubbs

Abstract

We have used fiber diffraction, cryo-electron microscopy, and scanning transmission electron microscopy to confirm the symmetry of three potexviruses, potato virus X, papaya mosaic virus, and narcissus mosaic virus, and to determine their low-resolution structures. All three viruses have slightly less than nine subunits per turn of the viral helix. Our data strongly support the view that all potexviruses have approximately the same symmetry. The structures are dominated by a large domain at high radius in the virion, with a smaller domain, which includes the putative RNA-binding site, extending to low radius.

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Citations

Jul 15, 2015·Nature Structural & Molecular Biology·Frank DiMaioEdward H Egelman
Mar 31, 2015·Virology·James N CulverReza Ghodssi
Jul 12, 2013·PloS One·Alexander L KsenofontovEugeny N Dobrov
Jun 26, 2017·Journal of Structural Biology·Duc H T LeNicole F Steinmetz
Feb 13, 2020·Current Protein & Peptide Science·Mattia SantoniLinda Avesani
Mar 7, 2019·Frontiers in Plant Science·Juliane RöderUlrich Commandeur
Mar 24, 2020·Nature Chemical Biology·Alessandro GrinzatoGiuseppe Zanotti

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