A Comparative Analysis of Clinical Characteristics and Histomorphologic and Immunohistochemical Spectrum of Gallbladder Carcinoma in Young Adults (< 45 Years) and Elderly Adults (> 60 Years).

Indian Journal of Surgical Oncology
Suneeta GuptaSukhpreet Kaur

Abstract

Gallbladder carcinoma (GBC) is more frequent after 60 years of age; its behavior in young adults has not been much studied. A retrospective analysis was performed in patients who underwent a cholecystectomy procedure between the years 2001 to 2016. A group of young patients (< 45) were compared with elderly patients (> 60 years) with reference to various clinical, histomorphologic, and immunohistochemical parameters. Statistical analysis was performed using t test and Fisher's test. Survival curves were calculated by Kaplan-Meier actuarial survival curves and log-rank tests. One hundred and one patients with GBC were observed during the study period. Of these, 14 patients (13.9%) belonged to the study group (age range 20 to 45 years) and 43 patients (42.6%) constituted the comparison elderly control group (age range 60 to 80 years). Forty-four pts. were in the middle-aged group (46 to 59 years) and were thus excluded from the study. With reference to age (< 45 and > 60), no significant difference was found in sex (females 64.3% vs 69.8%, p = 0.7), presence of gall stones (64% vs 60%, p = 0.8), advanced disease at presentation (T4) (14.3% vs 7%, p = 0.40), incidental detection of gallbladder carcinoma (28.5% vs 28%, p = 0.9), tu...Continue Reading

References

Jan 28, 2003·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·M Pandey
Jul 29, 2003·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·M Pandey, V K Shukla
Oct 30, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·G Miller, W R Jarnagin
Mar 12, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Luis A Hidalgo GrauJavier Suñol Sala
Sep 3, 2013·Indian Journal of Surgical Oncology·Sandeep SachidanandaJayanthi Venkataraman
Mar 25, 2014·Cancer Discovery·Emily PowellHelen Piwnica-Worms
Jun 10, 2016·Indian Journal of Surgical Oncology·Akash AgarwalSanjeev Misra
Jan 11, 2017·Indian Journal of Cancer·S S MhatreR Dikshit
Feb 22, 2017·Pathology, Research and Practice·Sung-Im DoKyungeun Kim
Jul 13, 2017·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Gopal GoyalSandeep Nijhawan
Aug 8, 2018·Indian Journal of Cancer·Rajeev Kumar MalhotraGourva Kishore Rath

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.