A comparative analysis of costs of single and dual rapid HIV and syphilis diagnostics: results from a randomised controlled trial in Colombia

Sexually Transmitted Infections
Carol Dayo ObureFreddy Perez

Abstract

HIV and congenital syphilis are major public health burdens contributing to substantial perinatal morbidity and mortality globally. Although studies have reported on the costs and cost-effectiveness of rapid diagnostic tests (RDTs) for syphilis screening within antenatal care in a number of resource-constrained settings, empirical evidence on country-specific cost and estimates of single RDTs compared with dual RDTs for HIV and syphilis are limited. A cluster randomised controlled study design was used to compare the incremental costs of two testing algorithms: (1) single RDTs for HIV and syphilis and (2) dual RDTs for HIV and syphilis, in 12 health facilities in Bogota and Cali, Colombia. The costs of single HIV and syphilis RDTs and dual HIV and syphilis RDTs were collected from each of the health facilities. The economic costs per woman tested for HIV and syphilis and costs per woman treated for syphilis defined as the total costs required to test and treat one woman for syphilis were estimated. A total of 2214 women were tested in the study facilities. Cost per pregnant woman tested and cost per woman treated for syphilis were US$10.26 and US$607.99, respectively in the single RDT arm. For the dual RDTs, the cost per pregna...Continue Reading

References

Oct 24, 2003·Sexually Transmitted Infections·F Terris-PrestholtR Hayes
Feb 26, 2004·Health Policy and Planning·Lesong Conteh, Damian Walker
May 31, 2007·PLoS Medicine·Bruce R SchackmanDaniel W Fitzgerald
Nov 28, 2013·Sexually Transmitted Infections·Amaya Sánchez-GómezWilliam Cevallos
May 13, 2015·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Fern Terris-PrestholtLori Newman
Oct 8, 2016·American Journal of Public Health·Islay RodríguezLola V Stamm
Nov 9, 2016·Bulletin of the World Health Organization·Naoko IshikawaMassimo Ghidinelli

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NCT02454816

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