A comparative analysis of two different sets of Y-chromosome short tandem repeats (Y-STRs) on a common population panel

Forensic Science International. Genetics
Julie L MaybruckPaul A Fuerst

Abstract

A comparative analysis of two Y-STR loci sets was conducted on a population sample of 224 individuals, 114 Caucasians and 110 African Americans. One set of loci, designated the OSU 10-locus set, comprises variable, single copy, male-specific loci that are dispersed across the Y-chromosome. Parallel evaluations were performed using the 10 Y-chromosome loci most frequently used for forensic analysis, the loci chosen as the SWGDAM Y-STR loci. The OSU 10-locus set had a greater average number of alleles per locus and higher average gene diversity than the SWGDAM loci. The OSU 10-locus set found 220 unique haplotypes in 224 individuals. In approximately 6000 pairwise haplotype comparisons for each population with each set of loci, the OSU 10-locus set also yielded a greater average number of allelic differences per pair than the SWGDAM loci. Finally, the overall linkage disequilibrium levels were lower for the OSU 10-locus set in the Caucasian population. In general, the OSU 10-locus set revealed a higher power of discrimination than the SWGDAM set.

References

Jan 1, 1994·Human Molecular Genetics·N MathiasC Tyler-Smith
Jan 1, 1996·Cytogenetics and Cell Genetics·N S MaJ Mao
Jan 1, 1997·International Journal of Legal Medicine·M KayserL Roewer
Jan 1, 1997·International Journal of Legal Medicine·P de KnijffL Roewer
Jul 6, 2000·International Journal of Legal Medicine·K AnslingerW Eisenmenger
Aug 15, 2000·Forensic Science International : Synergy·B M DupuyB Olaisen
Oct 16, 2001·International Journal of Legal Medicine·R IidaT Matsuki
Feb 20, 2002·Forensic Science International : Synergy·Elena BoschMark A Jobling
Dec 13, 2002·Forensic Science International : Synergy·Alan J ReddMichael F Hammer
Apr 18, 2003·European Journal of Human Genetics : EJHG·Ralf KittlerManfred Kayser
Mar 26, 2004·Forensic Science International : Synergy·Richard SchoskeJohn M Butler
Apr 9, 2004·International Journal of Legal Medicine·Harald NiederstätterWalther Parson
Jun 16, 2004·American Journal of Human Genetics·Manfred KayserChris Tyler-Smith
Feb 4, 2005·International Journal of Legal Medicine·M DiedericheL Gusmão
Apr 20, 2005·Forensic Science International : Synergy·Bruce BudowleBenjamin E Krenke
May 26, 2005·Forensic Science International : Synergy·L GusmãoUNKNOWN DNA Commission of the International Society of Forensic Genetics
Dec 13, 2005·Legal Medicine·Erin K Hanson, Jack Ballantyne
Feb 7, 2006·Forensic Science International : Synergy·Yuet Meng ChangDaniel L C Kuehn
Jun 2, 2006·The American Journal of Forensic Medicine and Pathology·Cheng-Lung LeeHenry C Lee
Jun 1, 2007·Forensic Science International. Genetics·Sascha WilluweitUNKNOWN International Forensic Y Chromosome User Group
Jan 1, 2008·Molecular Ecology Resources·François Rousset

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Citations

Aug 30, 2011·Forensic Science International. Genetics·Teresinha PalhaSidney Santos

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