A comparative developmental study of impulsivity in rats and humans: the role of reward sensitivity

Annals of the New York Academy of Sciences
Jatin G VaidyaDavid Watson

Abstract

The present study was conducted to test the hypothesis that differences in reward sensitivity between adolescents and adults account for differences in impulsivity. In a comparative study, we examined preferences for various concentrations of sucrose solutions as an operational measure of reward sensitivity in adolescent and adult rats and humans. Humans also completed self-report measures of impulsivity and reward sensitivity. There was some indication that adolescents preferred sweeter solutions compared to adults. Also, adolescents scored substantially higher on impulsivity. However, adolescents and adults did not differ in self-ratings of reward sensitivity and personality scores were not consistently related to sucrose preferences. The data highlight some of the benefits and issues that arise with developing comparative measures in humans and animals. Future comparative research using alternative behavioral paradigms is necessary to determine if and how changes in reward sensitivity influence developmental shifts in impulsivity.

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Citations

Jul 5, 2008·Psychopharmacology·Jennifer L Perry, Marilyn E Carroll
Jun 24, 2009·Psychopharmacology·Nicole L Schramm-SapytaCynthia M Kuhn
Jul 4, 2012·Psychopharmacology·Natalie E ZlebnikMarilyn E Carroll
Aug 12, 2008·Behavioural Pharmacology·Marilyn E CarrollNancy K Dess
Feb 24, 2016·Frontiers in Psychiatry·Marilyn E Carroll, John R Smethells
Apr 30, 2011·Neuroscience and Biobehavioral Reviews·David A Sturman, Bita Moghaddam
Jan 13, 2009·Drug and Alcohol Dependence·Marilyn E CarrollJennifer L Perry
May 15, 2007·Pharmacology, Biochemistry, and Behavior·Jennifer L PerryMarilyn E Carroll
Feb 24, 2015·Alcoholism, Clinical and Experimental Research·James M Doherty, Rueben A Gonzales
Jun 28, 2016·Addiction Biology·Marilyn E Carroll, Wendy J Lynch
Jul 15, 2017·PloS One·Andrew T MarshallSean B Ostlund
Oct 23, 2013·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Marci R MitchellBarry Setlow
Jan 1, 2009·Stress : the International Journal on the Biology of Stress·Angela J Grippo, Alan Kim Johnson
Jan 13, 2016·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Virginia D DriscollCarol P Olszewski
Sep 10, 2017·Developmental Psychobiology·Nicole E DeAngeliDavid J Bucci

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