A comparative evaluation of five hazard screening tools

Integrated Environmental Assessment and Management
Julie PankoA M Mason

Abstract

An increasing number of hazard assessment tools and approaches are being used in the marketplace as a means to differentiate products and ingredients with lower versus higher hazards or to certify what some call greener chemical ingredients in consumer products. Some leading retailers have established policies for product manufacturers and their suppliers to disclose chemical ingredients and their related hazard characteristics often specifying what tools to use. To date, no data exists that show a tool's reliability to provide consistent, credible screening-level hazard scores that can inform greener product selection. We conducted a small pilot study to understand and compare the hazard scoring of several hazard screening tools to determine if hazard and toxicity profiles for chemicals differ. Seven chemicals were selected that represent both natural and man-made chemistries as well as a range of toxicological activity. We conducted the assessments according to each tool provider's guidelines, which included factors such as endpoints, weighting preferences, sources of information, and treatment of data gaps. The results indicate the tools varied in the level of discrimination seen in the scores for these 7 chemicals and that ...Continue Reading

References

Aug 13, 1999·Toxicological Sciences : an Official Journal of the Society of Toxicology·E W CarneyM D Dryzga
Feb 23, 2013·BMJ Case Reports·Peter Ng
Jan 1, 2014·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·M-R GoldsmithC C Dary
Nov 8, 2014·Integrated Environmental Assessment and Management·Alison M GauthierErin Shay

❮ Previous
Next ❯

Citations

Dec 17, 2016·Integrated Environmental Assessment and Management·Julie PankoAnn M Mason
Dec 17, 2016·Integrated Environmental Assessment and Management·Michelle TurnerShari Franjevic
Mar 24, 2016·Integrated Environmental Assessment and Management·Angela L PerezJulie Panko
Jul 10, 2019·Integrated Environmental Assessment and Management·Haoyang HeJulie M Schoenung
Mar 16, 2017·Integrated Environmental Assessment and Management·Scott M ArnoldRosemary T Zaleski
Nov 18, 2018·Journal of Hazardous Materials·Haoyang HeJulie M Schoenung
Apr 20, 2021·Clean Technologies and Environmental Policy·Leora Vegosen, Todd M Martin
Aug 28, 2020·Environmental Science & Technology·Jakub KostalWill Raderman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Toxicology and Environmental Health. Part a
Seok KwonPetra Kern
Toxicological Sciences : an Official Journal of the Society of Toxicology
D R GermolecM I Luster
Clinical Pharmacology and Therapeutics
C KeipertABIRISK Consortium
© 2022 Meta ULC. All rights reserved