A Comparative Evaluation of the Sedative Effects of Nitrous Oxide-oxygen Inhalation and Oral Midazolam-Ketamine Combination in Children

International Journal of Clinical Pediatric Dentistry
IlasrinivasanPriya Mendiretta

Abstract

To compare nitrous oxide-oxygen inhalation and low dose oral midazolam-ketamine combination for anxiolysis in the management of children aged between 3 to 10 years for dental treatment. A comparative clinical study with equal number of subjects in both the groups evaluating efficacy of oral ketamine-midazolam combination and nitrous oxide-oxygen inhalation in children with Frankl behavior rating score 2 and ASA1.A total of 30 children were equally divided into 2 groups, oral midazolam-ketamine (MK) group which received 0.25mg/ kg midazolam with 3mg/kg ketamine in combination and the Nitrous oxide-oxygen (N) group which received nitrous oxide-oxygen inhalation. The parameters evaluated were the drug/ mask acceptance, need for the use of a physical restraint. Houpt's sedation scale, faces pain score, sedation duration, time taken to achieve the maximum sedation and adverse reactions were assessed. Student t-test was used for comparison between the groups and proportions were compared using Chi-square test. The results found no statistically significant differences between the groups in all the parameters except for the duration of sedation and the time taken to achieve maximum sedation which were higher in oral MK group than the ...Continue Reading

References

Apr 20, 2002·Anesthesiology·UNKNOWN American Society of Anesthesiologists Task Force on Sedation and Analgesia by Non-Anesthesiologists
Aug 30, 2002·International Journal of Paediatric Dentistry·B Peretz
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Jun 18, 2005·Paediatric Anaesthesia·Babita GhaiPramila Chari
May 6, 2009·Journal of the Indian Society of Pedodontics and Preventive Dentistry·A M Al-ZahraniS A Sheta
Jan 22, 2010·European Journal of Anaesthesiology·Ozgul BayginBerrin Isik
Nov 2, 2011·International Journal of Paediatric Dentistry·Mostafa SomriLuis A Gaitini
Mar 1, 2012·Dental Research Journal·Mojtaba Vahid GolpayeganiShahnaz Shayeghi
May 26, 2012·Australian Dental Journal·B ÖzenC Altun
Mar 8, 2013·International Journal of Paediatric Dentistry·Anni Birgitte GrønbækSven Poulsen

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