A comparative histopathological study of vocal fold polyps in smokers versus non-smokers

The Journal of Laryngology and Otology
K G Effat, M Milad

Abstract

A large proportion of patients with vocal fold polyps are cigarette smokers. However, prior to this report no comparative study of polyp histopathology in smokers versus non-smokers had been performed. A prospective histopathological study of vocal fold polyps excised from 29 patients was undertaken. This comprised a comparative analysis of polyp histopathology in smokers versus non-smokers and a review of the pertinent literature. Vocal fold polyps were larger in smokers than in non-smokers. Histopathological features significantly associated with the polyps of smokers versus those of non-smokers were increased keratinisation, dysplasia, a basement membrane thinning and hyaline degeneration. Cigarette smoke has an injurious effect on vocal fold polyp epithelium and leads to increased hyaline degeneration in polyps.

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Citations

Apr 8, 2020·Explore : the Journal of Science and Healing·Bong Hyun Kim, Hae Jeong Nam

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