A Comparative Split-Face Study Using Different Mild Purpuric and Subpurpuric Fluence Level of 595-nm Pulsed-Dye Laser for Treatment of Moderate to Severe Acne Vulgaris

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
Nataya VoravutinonMurad Alam

Abstract

Various forms of laser therapy including the pulsed-dye laser (PDL) have been reported to reduce acne lesion counts. In this study, the benefits and complications when using a 595-nm PDL for the treatment of acne vulgaris were evaluated when comparing a subpurpuric (low) fluence level with a purpuric (high) fluence level. This study was a prospective, single-blinded split-face clinical trial. Inclusion criteria included subjects with moderate to severe facial acne. All participants were treated with PDL, with each half of the face receiving either high or low fluence at 3-week intervals for a total of 4 treatments. Standardized facial photographs were obtained and blindly evaluated. Sixty-two subjects were enrolled with a mean age of 22.3 years. Fifty-five patients completed the study. The results showed a significant decrease in lesion counts compared with baseline after all treatments. However, the study did not demonstrate a statistically significant difference between the fluence parameters. The only treatment-related adverse event was temporary hyperpigmentation. This study demonstrates that PDL is effective in reducing acne lesions using purpuric and subpurpuric fluences. However, there was no statistically significant di...Continue Reading

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Citations

Sep 28, 2016·The Cochrane Database of Systematic Reviews·Jelena BarbaricJosip Car
Feb 15, 2018·Journal of the European Academy of Dermatology and Venereology : JEADV·F M C de VriesP C M van de Kerkhof
Apr 20, 2019·Journal of Cosmetic Dermatology·Emily Forbat, Firas Al-Niaimi
Aug 5, 2017·Lasers in Medical Science·Lauren E WizniaArielle R Nagler
Nov 5, 2019·Pediatrics in Review·Rosalind Ashton, Miriam Weinstein
Nov 24, 2020·Journal of Cosmetic Dermatology·Napith ChalermsuwiwattanakanMontree Udompataikul
Jun 10, 2020·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·Martin KassirMohamad Goldust
Jul 22, 2021·American Journal of Clinical Dermatology·Monica K LiJeffrey T S Hsu
Dec 20, 2021·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Ting-Hua YangYu-Chen Huang

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