A comparative study of incorporation rates between non-xenograft and bovine-based structural bone graft in foot and ankle surgery

The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons
Naohiro ShibuyaDaniel C Jupiter

Abstract

Several types of structural bone grafts are available, each with different characteristics. Our previous study showed poor performance with the bovine-based xenograft in foot and ankle applications. In the present study, we compared the incorporation rates of non-xenografts, including allografts and autografts, with the bovine-based xenograft to determine whether the poor result was unique to the graft type and not institutional. The proportion of incorporated grafts at 12, 24, 36, and 48 weeks was compared between the nonxenograft and xenograft groups. Furthermore, Cox regression analysis was used to evaluate the factors associated with nonunion. A total of 61 patients (23 women and 38 men) with a median age of 24.0 years were enrolled. The factors associated with slower incorporation included side of operation (p = .033), tobacco use (p = .010), and graft type (p = .001). At 48 weeks, 5% of the nonxenografts and 58% of the xenografts were not incorporated. The median incorporation time for the non-xenograft and xenograft group was 16 and 57 weeks, respectively. We have concluded that it is not advisable to use a bovine-based bone xenograft in foot and ankle surgery.

References

Jul 1, 1985·Journal of Pediatric Orthopedics·R E McCallF A Johnston
Jan 1, 1994·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·K J Stevens, M Banuls
Jun 6, 1998·Journal of the American Podiatric Medical Association·K T Mahan, H J Hillstrom
Oct 25, 2003·Clinical Implant Dentistry and Related Research·Giovanni Cricchio, Stefan Lundgren
Feb 14, 2007·Foot & Ankle International·Loretta B ChouMark S Mizel
Sep 3, 2008·The Journal of Bone and Joint Surgery. American Volume·Luis A CorralesTheodore Miclau
May 9, 2013·Journal of Pediatric Orthopedics·Cameron K LedfordRobert K Lark

❮ Previous
Next ❯

Citations

Dec 3, 2014·Clinics in Podiatric Medicine and Surgery·Naohiro Shibuya, Daniel C Jupiter
Nov 26, 2019·Xenotransplantation·Xiaohang LiChristopher Burlak

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

Related Papers

The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons
Naohiro ShibuyaJavier La Fontaine
The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons
M H HofbauerM L Scripps
Journal of Pediatric Orthopedics
Cameron K LedfordRobert K Lark
© 2021 Meta ULC. All rights reserved