Jan 1, 1986

A comparative study of specificity of the intestinal Na+/sugar cotransport among vertebrates

Comparative Biochemistry and Physiology. A, Comparative Physiology
T Shimada, T Hoshi

Abstract

Kt values for various monosaccharides were determined from sugar-induced increments of the transmural potentials in isolated small intestines of the goldfish, bullfrog, turtle, quail, guinea pig, rat and rabbit, and specificity patterns of the Na+/sugar cotransporters were compared among these animal species. Absolute requirement of the D-pyranose ring structure was seen in all animals. Requirements of C2-OH and C6 were strong, but not absolute, and OH groups on C3, C4, C6 and the O-atom of the pyranose ring were also suggested to participate, in some degree, in the interaction with the carrier. Comparison of the disaccharide-evoked potentials revealed that there were considerable species differences in activities of trehalase, sucrase and lactase among animals examined, but the differences were relatively small for maltase activity.

  • References12
  • Citations7

References

  • References12
  • Citations7

Mentioned in this Paper

Vertebrates
Cavia
August Rats
TREH gene
Disaccharides
Chinchilla Rabbits
Substrate Specificity
Hexose Transporter
Evoked Potentials
Trehalase

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