A Comparative Study of Surgical Splenectomy, Partial Splenic Embolization, and High-Intensity Focused Ultrasound for Hypersplenism

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
Jing ZhuChao He

Abstract

This study compared splenectomy, partial splenic embolization, and high-intensity focused ultrasound (HIFU) therapy, which represent the traditional, mature, and newest methods for improving thrombocytopenia in hypersplenism, respectively. A total of 69 patients with hypersplenism were treated with surgical splenectomy (n = 31), HIFU (n = 26), or partial splenic embolization (n = 12). They were followed closely for at least 6 months, and the effectiveness of the treatments was compared. Among the 3 groups, splenectomy was the most effective treatment for increasing peripheral blood cells. Embolization reduced the operating time and hospital stay, but HIFU was relatively safer and less invasive than the other treatments. High-intensity focused ultrasound has wide clinical indications for hypersplenism and may be safer than other treatment methods. Therefore, it is a good alternative procedure for patients with a high surgical risk.

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Citations

Jul 10, 2016·Asian Pacific Journal of Tropical Medicine·Gui-Yun JinChao-Qian Li
Jul 25, 2019·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Yanhao WangJianzhong Zou
Jul 1, 2019·Journal of Minimally Invasive Gynecology·Suhua ShiZhimin Ding
Dec 15, 2020·World Journal of Hepatology·Saad Emhmed AliAnna Christina Dela Cruz
Feb 6, 2020·Journal of Vascular and Interventional Radiology : JVIR·Abhinav TalwarRiad Salem

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