PMID: 8599259Jan 1, 1995Paper

A comparative study of two near infrared spectrophotometers for the assessment of cerebral haemodynamics

Acta Anaesthesiologica Scandinavica. Supplementum
W N ColierB Oeseburg

Abstract

Conventional near infrared spectroscopy (NIRS), introduced by Jöbsis in 1977, can be considered as a reliable trend monitor for cerebral oxygenation. Quantisation, however, is complex and cumbersome. Recently a relatively simple system for cerebral oximetry (INVOS 3100, Somanetics Corporation, USA) was developed, measuring the regional oxygen saturation (rSO2) in the capillary bed of the cerebrum, presented as a numerical figure for easy interpretation. In this study a comparison was made between a conventional NIRS instrument and the new INVOS instrument, in order to obtain information about sensitivity and usefulness of the INVOS system. Changes in cerebral haemodynamics were induced by a moderate decrease of the arterial oxygen saturation (SaO2) and by varying the arterial carbon dioxide level (PaCO2). This will result in a higher (hypercapnia) or lower (hypocapnia) cerebral blood flow and subsequent change of both NIRS signals and INVOS signal. Healthy volunteers were used for this study. It was found that the steady state value for rSO2 was 70 +/- 6% (mean +/- SD). During the lowering of arterial saturation a poor correlation was found between rSO2 and SaO2 (r = 0.47). Increased cerebral blood flow induced by hypercapnia w...Continue Reading

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Citations

Jan 5, 2011·Journal of Biomedical Optics·Daniel S GareauSteven L Jacques
Aug 26, 1998·Journal of Cardiothoracic and Vascular Anesthesia·J W de VriesP F Bakker
Jul 25, 2015·Journal of the American Society of Hypertension : JASH·Hercules GrantAnthony Singhal
Apr 13, 2013·NeuroImage·Ann-Christine EhlisAndreas J Fallgatter
Jan 30, 2014·Scientific Reports·Gregory L WillisStuart Maxwell Armstrong
Sep 24, 2005·Journal of Biomedical Optics·David A BenaronEben L Kermit
Nov 10, 1998·Anaesthesia and Intensive Care·C D GomersallT E Oh
Oct 20, 2001·Journal of Applied Physiology·S HoutmanM T Hopman
Oct 24, 2017·Human Brain Mapping·Ali KassabDang Khoa Nguyen

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