A comparative study of Zingiber officinale Roscoe pulp and peel: phytochemical composition and evaluation of antitumour activity

Natural Product Research
Mariangela MarrelliFilomena Conforti

Abstract

Colon cancer is one of the major causes of cancer mortality worldwide. Hydroalcoholic extract of ginger peel extract was more potent against colon cancer cells than ginger pulp hydroalcoholic extract using MTT assay, while ginger pulp hydroalcoholic extract showed higher anti-inflammatory and antioxidant activities. The two samples of ginger showed a different polyphenolic content and lipophilic composition. Peel extract possessed twice the polyphenolic content than pulp and the highest number of non-polar compounds. Among them, α-zingibirene was found to be the major constituent. The findings add to epidemiologic evidence for therapeutic effects of ginger peel in colorectal carcinoma.

References

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Citations

Feb 24, 2016·Natural Product Research·Sirichan Tachai, Nuchnipa Nuntawong
Mar 3, 2018·International Journal of Molecular Sciences·Monika Gorzynik-DebickaMagdalena Gorska-Ponikowska
Nov 6, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mariangela MarrelliPinarosa Avato
May 8, 2020·Oxidative Medicine and Cellular Longevity·Paola AielloWesam Kooti
Aug 10, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·John F Lechner, Gary D Stoner
Jan 12, 2021·Frontiers in Molecular Biosciences·Savariar VincentManoj Dhanraj
Sep 10, 2017·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Bassem Y SheikhAmin Ismail
May 7, 2021·Natural Product Research·Mariangela MarrelliFilomena Conforti
Oct 17, 2020·Chemistry & Biodiversity·Mariangela MarrelliFilomena Conforti

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