PMID: 6167243Jan 1, 1980Paper

A comparative study on basophil histamine release and skin testing in children with allergic rhinitis

Archivum Immunologiae Et Therapiae Experimentalis
W KazimierczakD Szabelska

Abstract

Skin tests and histamine release from basophils induced by the same allergens in children with allergic rhinitis were compared. A qualitative correlation between these two tests was found. Basophil histamine release either spontaneous or allergen-induced during the period of developed allergic symptoms was markedly higher as compared with that in a period of clinical remission. It is concluded that basophil histamine release might be a valuable diagnostic method for detection of allergen(s) responsible for symptoms of allergic rhinitis.

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