A comparative study on psycho-socio-demographic and clinical profile of patients with bipolar versus unipolar depression

Indian Journal of Psychiatry
A NishaP Joseph Varghese

Abstract

Several studies have revealed significant differences between bipolar (BP) and unipolar depression (UP). Misdiagnosing BP depression results in suboptimal symptom resolution, induction of manic switch, mixed state, or accelerated cycling. This study compares various psycho-socio-demographic, longitudinal course, and phenomenological factors associated with BP and UP depression. We compared 30 UP and 30 BP depression patients using a specially designed intake proforma, International Classification of Diseases-10 diagnostic criteria for research, Hamilton Rating Scale for Depression-21 (HAMD-21), Hypomania Checklist-32 Questionnaire (HCL-32), Brief psychiatric rating scale (BPRS), and Kuppuswami's socioeconomic status scale. BP depression group consisted of mostly males, with earlier age of onset of illness, longer illness duration, frequent episodes, hospitalizations and psychotic symptoms. The total HAM-D score and 4 HAM-D item scores-psychomotor retardation, insight, diurnal variation of symptoms and its severity, and paranoid symptoms were significantly higher in this group. Binary logistic regression identified the age of onset, the total duration of illness, frequency of affective episodes, and presence of delusions as pred...Continue Reading

References

Aug 1, 1995·The American Journal of Psychiatry·L L AltshulerL Ackerman
Jun 5, 1999·Journal of Affective Disorders·S N GhaemiK Goodwin
Oct 19, 1999·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·J R CalabreseM D Shelton
Aug 2, 2001·The Journal of Clinical Psychiatry·S G Kornstein, R K Schneider
Aug 2, 2001·The American Journal of Psychiatry·J F GoldbergJ E Whiteside
Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
Mar 12, 2004·Primary Care Companion to the Journal of Clinical Psychiatry·J Sloan ManningDonald P. Hay
Jun 9, 2005·Archives of General Psychiatry·Ronald C KesslerEllen E Walters
Aug 30, 2005·Journal of Affective Disorders·Jules AngstJan Scott
Feb 2, 2006·The American Journal of Psychiatry·Roy H PerlisAndrew A Nierenberg
May 3, 2008·The British Journal of Psychiatry : the Journal of Mental Science·Liz FortyNick Craddock

❮ Previous
Next ❯

Software Mentioned

Statistical Package for Social Sciences ( SPSS

Related Concepts

Related Feeds

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.