A comparison between TNM and TANIS stage grouping for predicting prognosis of oral and oropharyngeal cancer

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
F CarinciC Calearo

Abstract

The 1987 TNM classification system modified some T and N definition but it did not change stage grouping. Consequently it has not improved the prognostic validity of the advanced stage groups. In 1993, a new stage grouping was purposed, TANIS, that seems to have a higher correlation with survival. In this report, the TNM classification and TANIS system were compared to evaluate this prognostic ability. Data from 164 patients affected by primary cancers of oropharynx or oral cavity were analyzed by means of Kaplan-Meier and Cox regression analysis. The crude survival rate at 5 years was 43.9%. Both systems showed a significant correlation with the survival rate by means of Cox regression analysis. TANIS subcategories were correlated to the mortality rate in the stage IV patients. TANIS resulted a better predictor of mortality when compared with TNM. The TANIS system was able to separate the TNM stage IV patients into prognostic groups, yielding more information with respect to TNM for such a category of patients. When a comparison between TNM and TANIS was performed, it was observed that TANIS had a higher correlation with survival rate, whereas TNM did not add any information in defining the survival function.

Citations

Jun 14, 2002·Journal of Clinical Epidemiology·Patti A GroomeRandy J Bissett
Jul 10, 2001·Head & Neck·W M LydiattUNKNOWN Head and Neck Sites Task Force. American Joint Committee on Cancer
Sep 28, 2010·Journal of Surgical Oncology·Matthias KreppelMartin Scheer
Jan 2, 2003·Head & Neck·Kirsten HannisdalJan F Evensen
Sep 20, 2011·Head & Neck·Matthias KreppelJoachim E Zöller
Apr 21, 2001·The Journal of Craniofacial Surgery·F CarinciA Pastore
May 22, 2008·Journal of Surgical Oncology·Snehal G Patel, William M Lydiatt
Mar 2, 2010·Head & Neck·Robert P TakesAlfio Ferlito
Apr 26, 2017·Journal of Maxillofacial and Oral Surgery·Panagiotis Stathopoulos, William P Smith
Jul 25, 2006·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Paolo Garzino-DemoMarina Schena

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