A comparison between volumetric data generated by voxel-based morphometry and manual parcellation of multimodal regions of the frontal lobe.

AJNR. American Journal of Neuroradiology
O LindbergL O Wahlund

Abstract

Volumetric measurements on structural MR images are an established method to investigate pathology-related volume changes in cortex. Manual volumetric methods have sometimes been referred to as the reference standard for quality control of automatic volumetric methods. While some automatic methods, like VBM, may rely on a template, manual methods use sulci as indirect landmarks for the subdivision of cortex. The purpose of this study was to compare volumetric data generated by MM and VBM on 4 multimodal regions in the frontal lobe. We investigated 4 multimodal frontocortical regions by MM and VBM in patients with frontotemporal lobar degeneration and Alzheimer disease and controls. MM and VBM results were highly correlated for dorsolateral prefrontal cortex, orbitofrontal cortex, and hippocampus, but not for the dorsal and rostral anterior cingulate. VBM results were more consistent with results from previous studies on cingulate in frontotemporal lobar degeneration. Our results may potentially be explained by 2 factors. First, the volume of small cortical regions may be more affected by anatomic variability than large regions in the MM. Second, it has been shown that the location of multimodal cytoarchitectonic areas, such as ...Continue Reading

References

Jul 2, 1998·Brain : a Journal of Neurology·M M Mesulam
Apr 19, 2000·Human Brain Mapping·J AshburnerK J Friston
Dec 7, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J EritaiaC Pantelis
Dec 15, 2000·Psychiatry Research·B Crespo-FacorroV A Magnotta
Aug 23, 2001·Medical Image Analysis·M Jenkinson, S Smith
Oct 23, 2002·Human Brain Mapping·Stephen M Smith
Oct 19, 2004·Canadian Journal of Nursing Leadership·R J Burke
Oct 27, 2004·NeuroImage·Stephen M SmithPaul M Matthews
Jun 3, 2005·Brain : a Journal of Neurology·Michio SuzukiMasayoshi Kurachi
Jul 25, 2006·NeuroImage·Laurie M McCormickMichael Brumm
Nov 8, 2006·Topics in Magnetic Resonance Imaging : TMRI·Jennifer L Whitwell, Clifford R Jack
Dec 26, 2006·Annals of Neurology·William W SeeleyStephen J Dearmond
May 12, 2007·Psychiatry Research·Nikolai V MalykhinRichard Camicioli
Sep 18, 2007·NeuroImage·K AmuntsK Zilles
Dec 15, 2007·Cerebral Cortex·Bruce FischlKarl Zilles
Feb 13, 2008·Archives of Neurology·William W SeeleyMaria Luisa Gorno-Tempini
Apr 4, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Philip ShawSteve P Wise
Sep 11, 2008·AJNR. American Journal of Neuroradiology·J C L LooiL-O Wahlund
Apr 7, 2009·AJNR. American Journal of Neuroradiology·O LindbergL-O Wahlund
Apr 21, 2009·Neuron·William W SeeleyMichael D Greicius
Jul 3, 2009·Neurobiology of Aging·Kristine B WalhovdAnders M Fjell
Oct 1, 2010·Reviews in the Neurosciences·Anders M Fjell, Kristine B Walhovd
Jan 29, 2011·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Maria Carmela TartagliaBruce L Miller
Aug 16, 2011·Brain Topography·Scott M McGinnisBradford C Dickerson

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Citations

Feb 11, 2015·Psychiatry Research·Csilla SzabóSzabolcs Kéri
Nov 13, 2015·European Radiology·Daniel FerreiraUNKNOWN AddNeuroMed consortium and for the Alzheimer’s Disease Neuroimaging Initiative*
Oct 16, 2015·Journal of Computer Assisted Tomography·Simon R CoxKaren J Ferguson

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