A comparison of 0.0625% bupivacaine with fentanyl and 0.1% ropivacaine with fentanyl for continuous epidural labor analgesia

Anesthesia and Analgesia
J Fernández-GuisasolaS G Del Valle

Abstract

We compared the analgesic efficacy and the degree of motor block achieved with epidural infusion of 0.0625% bupivacaine (Group B) versus 0.1% ropivacaine (Group R), both with 0.0002% fentanyl (2 microg/mL) in laboring patients. A prospective, double-blinded study was performed in 98 ASA physical status I-II parturients who were divided randomly into two groups to receive either bupivacaine or ropivacaine after catheter location had been tested with an initial bolus of lidocaine and fentanyl. The infusion rate was 15 mL/h in every case. When pain was perceived, 5-mL boluses of the assigned epidural analgesic were administered every 10 min until analgesia was achieved. We recorded pain intensity, level of sensory block, degree of motor block, hemodynamic variables, secondary effects, mode of delivery, neonatal outcome, and patient satisfaction. There were no statistically significant differences in any of the factors analyzed. Highly effective analgesia was achieved in both groups with a small incidence of motor block. These findings suggest that bupivacaine may be more potent than ropivacaine. We compared different concentrations of epidural bupivacaine and ropivacaine thought to be equipotent. Both solutions were equally effici...Continue Reading

References

Mar 1, 1995·British Journal of Anaesthesia·A F McCraeJ H McClure
Jun 1, 1997·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·H A MuirA Macarthur

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Citations

Apr 26, 2002·Anesthesia and Analgesia·Luis CasatiMargarita M Puig
Apr 23, 2003·Anesthesia and Analgesia·Stephen H Halpern, Vivien Walsh
Mar 31, 2015·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Yiyang LiHongmei Xu
Dec 23, 2004·Paediatric Drugs·Giorgio Capogna, Michela Camorcia
Nov 15, 2001·Current Opinion in Obstetrics & Gynecology·A Thallon, A Shennan
Aug 8, 2018·The Journal of Obstetrics and Gynaecology Research·Yang ZhangLiang-Tu Hui

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