PMID: 753616Jan 1, 1978Paper

A comparison of 99Tc and 123I scintigraphy in nodular thyroid disorders

European Journal of Nuclear Medicine
H Dige-PetersenN O Roy-Poulsen

Abstract

Out of 450 patients referred for thyroid scintigraphy 83 consecutive patients with nodular goitre were selected for dual scintigraphy with 99mTc and 123I. Seventy-four patients had one or more palpable nodules and the other nine patients had palpably diffuse goitres with one or more nodules on the routine 99mTc scintigram. For the comparison of scintigrams an eight level colour display was used, and regional differences between the 99mTc and 123I scintigrams were defined as a minimum of 25% (2 colour levels) variation of the relative activity in well defined areas. Thirteen patients, i.e. 16% of those with nodular goitre, had discordant scintigrams. All 13 patients had non-malignant thyroid disorders, (simple goitre, radio-iodine treated hyperthyroidism, autonomous adenoma, subacute thyroiditis, Riedel's and lymphocytic thyroiditis). The diagnosis was verified histologically in eight of these patients. Eight of the 13 patients had a high 99mTc activity relative to 123I, five patients showed the opposite discrepancy. Another 5 patients with a follicular or mixed follicular thyroid carcinoma had identical scintigrams. These findings indicate that 123I does not offer such diagnostic advantages over the cheap and readily available ...Continue Reading

Citations

Apr 1, 1980·European Journal of Nuclear Medicine·T HaradaT Senoo
Apr 1, 1981·European Journal of Nuclear Medicine·B ShapiroS Poston
Apr 1, 1987·Journal of Endocrinological Investigation·J D Wiener
Feb 24, 2006·Clinical Nuclear Medicine·Ozhan OzdoganHatice Durak
Feb 18, 2003·Endocrine Reviews·Laszlo HegedüsFinn N Bennedbaek
Apr 27, 2012·The Journal of Small Animal Practice·R E ShielC T Mooney

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Thyroiditis

Autoimmune thyroiditis is an inflammatory disease of thyroid gland due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-cells and thyroid autoantibodies. Discover the latest research on autoimmune thyroiditis here.