A comparison of antidepressant use in Nova Scotia, Canada and Australia

Pharmacoepidemiology and Drug Safety
Alesha J SmithSusan E Tett

Abstract

The prevalence of major depression is reported as approximately 8% in Canada and 7.5% in Australia, the use of antidepressants is therefore common. However, questions remain about whether depression is under-diagnosed and whether patients are appropriately treated with antidepressants once the disorder is recognized. We compared the use of antidepressant medicines, in Nova Scotia, Canada and Australia, in populations receiving public drug subsidy. The Nova Scotia Pharmacare Program and the Pharmaceutical Benefits Scheme in Australia were used to obtain dispensing data for all publicly subsidized antidepressants. Utilization was compared from 2000-2003, using the World Health Organisation Anatomic Therapeutic Chemical (ATC)/Defined Daily Dose (DDD) system. The use of antidepressants increased in both areas over the study period. However, the use of antidepressants in Nova Scotia increased at a significantly higher rate than Australia. Selective serotonin reuptake inhibitors (SSRIs) were the most commonly prescribed class of drugs in both areas, constituting 60% of all antidepressants prescribed. Eight different antidepressants made up 90% of the antidepressant drug use in Australia, with sertraline the most commonly prescribed. ...Continue Reading

References

Oct 1, 1994·Academic Medicine : Journal of the Association of American Medical Colleges·J MonetteR Laprise
Jun 17, 1998·European Journal of Clinical Pharmacology·U BergmanF Sjöqvist
Jun 5, 1999·Journal of Affective Disorders·S V ParikhP N Goering
May 2, 2000·The British Journal of Psychiatry : the Journal of Mental Science·K C WilsonC F McCracken
Aug 11, 2000·BMJ : British Medical Journal·S M CampbellD Roberts
Oct 5, 2001·Health Affairs·D J BirkettP McManus
Jan 29, 2002·Current Pharmaceutical Design·S E Buffett-Jerrott, S H Stewart
Mar 6, 2003·Pharmacoepidemiology and Drug Safety·Rolf van HultenHubert G Leufkens
Jun 19, 2003·JAMA : the Journal of the American Medical Association·Ronald C KesslerUNKNOWN National Comorbidity Survey Replication
Oct 3, 2003·Pharmacoepidemiology and Drug Safety·Björn WettermarkUlf Bergman
Feb 6, 2004·Quality & Safety in Health Care·C Paton, P Lelliott
May 7, 2004·Acta Psychiatrica Scandinavica. Supplementum·J AlonsoUNKNOWN ESEMeD/MHEDEA 2000 Investigators, European Study of the Epidemiology of Mental Disorders (ESEMeD) Project
Jun 17, 2004·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Scott B Patten, Cynthia Beck
Sep 1, 2004·The American Journal of Psychiatry·Gregory E SimonUNKNOWN LIDO Group
Sep 17, 2004·The Australian and New Zealand Journal of Psychiatry·Jeffrey C RichardsIan B Hickie
Sep 24, 2004·Pharmacoepidemiology and Drug Safety·Dustin D FrenchDavid M Angaran
Sep 28, 2004·European Journal of Clinical Pharmacology·Arcangelo CiunaCorrado Barbui
Oct 7, 2004·The Medical Journal of Australia·Andrea MantIan B Hickie
Jan 28, 2005·Psychosomatic Medicine·Stephen Kisely, Gregory Simon
Mar 22, 2005·The Australian and New Zealand Journal of Psychiatry·Anthony F JormKathleen M Griffiths
Apr 14, 2005·International Journal of Psychiatry in Medicine·Enric AragonèsNúria Mèlich
Jun 23, 2005·Current Medical Research and Opinion·Eric Michael Kaplan, Robert L DuPont
Jul 16, 2005·Journal of Affective Disorders·Anthony F JormKathleen M Griffiths
Oct 1, 2005·International Review of Psychiatry·C Ineke Neutel
Nov 10, 2005·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Jill M StarkesStephen R Kisely
Nov 24, 2005·Family Practice·John BushnellUNKNOWN MaGPIe Research Group
Jan 18, 2006·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Jitender SareenMurray B Stein
Jan 18, 2006·Lancet·Klaus P EbmeierJ Douglas Steele
Apr 14, 2006·Cleveland Clinic Journal of Medicine·Elias A KhawamDonald A Malone
May 13, 2006·Age and Ageing·Duncan Robert PettyArnold Zermansky
Nov 23, 2006·Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists·Robert Goldney, Marcus Bain
Jan 4, 2007·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Alicia Priest
Jan 12, 2007·Psychiatric Services : a Journal of the American Psychiatric Association·Helen-Maria VasiliadisRonald C Kessler
Feb 9, 2007·Pharmacoepidemiology and Drug Safety·Scott B PattenBrian Carter
Feb 22, 2007·Clinical Orthopaedics and Related Research·Sanjo Adeoye, Kevin J Bozic
Sep 4, 2008·BMJ : British Medical Journal·Barbara Mintzes

❮ Previous
Next ❯

Citations

Jun 29, 2010·Primary Care Companion to the Journal of Clinical Psychiatry·Elisa Martín-MerinoLuis A García-Rodriguez
Feb 2, 2016·Forensic Science International : Synergy·Olaf H Drummer, Suwan Yap
Jan 23, 2016·BMC Public Health·Izabela FuloneLuciane Cruz Lopes
Jul 24, 2010·Australian and New Zealand Journal of Public Health·Penny BuykxAlison Ritter
Apr 6, 2013·Pharmacoepidemiology and Drug Safety·Susan E TettNadia Barozzi
Aug 1, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Cassia SacchetAngelo L Piato
Aug 23, 2016·Drug Development Research·Natasa Bogavac-Stanojevic, Dragana Lakic
Jan 29, 2018·Journal of Neural Transmission·Yasmin Busch, Andreas Menke
Aug 2, 2015·Clinical Journal of the American Society of Nephrology : CJASN·Christel RenouxUNKNOWN Canadian Network of Observational Drug Effect Studies (CNODES) Investigators
Nov 26, 2011·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Chiranjeev SanyalPantelis Andreou
May 10, 2017·The Australian and New Zealand Journal of Psychiatry·Amanda L StuartLana J Williams
Feb 2, 2021·Canadian Journal of Physiology and Pharmacology·Ahmed Ayyash, Alison C Holloway

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Drug and Alcohol Review
A Mant, R A Walsh
International Journal of Psychiatry in Medicine
Enric AragonèsNúria Mèlich
The Annals of Pharmacotherapy
Remo OstiniSusan E Tett
Current Medical Research and Opinion
Eric Michael Kaplan, Robert L DuPont
© 2021 Meta ULC. All rights reserved