A comparison of APACHE II, BISAP, Ranson's score and modified CTSI in predicting the severity of acute pancreatitis based on the 2012 revised Atlanta Classification

Gastroenterology Report
Anubhav Harshit Kumar, Mahavir Singh Griwan

Abstract

Our aim was to prospectively compare the Accuracy of Acute Physiology and Chronic Health Evaluation (APACHE) II, Bedside Index of Severity in Acute Pancreatitis (BISAP), Ranson's score and modified Computed Tomography Severity Index (CTSI) in predicting the severity of acute pancreatitis based on Atlanta 2012 definitions in a tertiary care hospital in northern India. Fifty patients with acute pancreatitis admitted to our hospital during the period of March 2015 to September 2016 were included in the study. APACHE II, BISAP and Ranson's score were calculated for all the cases. Modified CTSI was also determined based on a pancreatic protocol contrast enhanced computerized tomography (CT). Optimal cut-offs for these scoring systems and the area under the curve (AUC) were evaluated based on the receiver operating characteristics (ROC) curve and these scoring systems were compared prospectively. Of the 50 cases, 14 were graded as severe acute pancreatitis. Pancreatic necrosis was present in 15 patients, while 14 developed persistent organ failure and 14 needed intensive care unit (ICU) admission. The AUC for modified CTSI was consistently the highest for predicting severe acute pancreatitis (0.919), pancreatic necrosis (0.993), orga...Continue Reading

References

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Citations

Mar 22, 2019·The Journal of Immunology : Official Journal of the American Association of Immunologists·Ruling ZhangJing Xue
Aug 15, 2018·Journal of Clinical Gastroenterology·Zhouxiang JinJisheng Wang
Sep 9, 2019·Abdominal Radiology·Stephanie D ColvinKristin K Porter
Oct 31, 2019·The Journal of International Medical Research·Xiaojuan WangZhiqiang Du
Jan 18, 2020·International Journal of Molecular Sciences·Pedro Silva-VazJosé Guilherme Tralhão
May 20, 2020·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Ramin NiknamFardad Ejtehadi
Oct 19, 2019·Journal of Clinical Medicine·Jorge PaulinoFilipe Veloso Gomes
Nov 26, 2020·The British Journal of Radiology·Yi WangBin Song
Jan 9, 2021·Immunity, Inflammation and Disease·Xingxing YuHeguang Huang
May 22, 2020·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Subramani Kandasamy
Jul 27, 2021·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Jia TangXia Chen
Jul 5, 2021·Acta Gastro-enterologica Belgica·A R BaykanM Senyurt
Nov 11, 2021·European Journal of Pain : EJP·Mária FöldiUNKNOWN Hungarian Pancreatic Study Group

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