A comparison of clinical-pathological characteristics between symptomatic and interval breast cancer

The Breast : Official Journal of the European Society of Mastology
B MeshkatE W McDermott

Abstract

An association between interval breast cancers (cancer detected after a normal mammogram and before the next scheduled mammogram) and tumour aggressiveness has been postulated which may reflect their relatively poor overall prognosis. The aim of this study was to evaluate known prognostic features of screen detected breast cancers compared to interval breast cancers. Patients diagnosed with breast cancer between January 2010 and 2013 at a single unit of the National Breast Screening Program (NBSP) in Ireland and those between the ages of 50 and 65 diagnosed at a symptomatic breast clinic were included in the study. Patients who had not had a screening mammogram within the proceeding two years or had a previous history of breast cancer were excluded. Data were retrospectively collected on patient demographics, tumour type, grade, hormone receptor status and stage of disease at presentation. There were 915 patients included in the study, with 92% (n = 844) diagnosed through the NBSP. Ductal carcinoma in-situ accounted for 19% (n = 160) of screen-detected breast cancers but only 2.8% of interval cancers (p < 0.05). The most common type of invasive cancer was invasive ductal carcinoma. Tumour grade was significantly higher in inter...Continue Reading

References

May 1, 1979·AJR. American Journal of Roentgenology·J E MartinJ R Milbrath
May 20, 1992·Journal of the National Cancer Institute·L MaN F Boyd
Jan 1, 1987·Breast Cancer Research and Treatment·J FrisellA Somell
Mar 27, 1996·JAMA : the Journal of the American Medical Association·V L ErnsterC Henderson
Jul 1, 1992·The International Journal of Health Planning and Management·D W Taylor, E Little
Oct 17, 2002·Journal of the National Cancer Institute·Virginia L ErnsterBerta M Geller
Jul 26, 2003·Annals of Oncology : Official Journal of the European Society for Medical Oncology·H J de Koning
Sep 2, 2004·JAMA : the Journal of the American Medical Association·Heikki JoensuuJohan Lundin
Sep 30, 2004·The Breast : Official Journal of the European Society of Mastology·J G MollandD J Gillett
Aug 18, 2005·Journal of the National Cancer Institute·Yu ShenDonald A Berry
Jan 19, 2010·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Bert van der VegtGeertruida H de Bock
Feb 18, 2010·Annals of Surgical Oncology·Nabil WasifArmando E Giuliano
Feb 26, 2011·Journal of the National Cancer Institute·Stella MookMarjanka K Schmidt
Nov 2, 2011·Breast Cancer Research and Treatment·Jiyoung KimJung-Hyun Yang
May 16, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Antonino MusolinoAndrea Ardizzoni
Jun 14, 2012·Ecology·Who-Seung LeeNeil B Metcalfe
Jun 22, 2013·Breast Cancer Research : BCR·Louise ErikssonPer Hall
Jan 18, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·N L P BarnesN J Bundred
Mar 13, 2014·International Journal of Cancer. Journal International Du Cancer·Teresa ToAnthony B Miller
Mar 22, 2014·Biomedical Reports·Shu Guang Li, Li Li

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Citations

Jun 19, 2016·The Breast : Official Journal of the European Society of Mastology·Jacques Bernier, Philip M P Poortmans
Apr 7, 2018·Journal of Medical Imaging and Radiation Oncology·Jennifer Stone
Feb 13, 2019·The Journal of Pathology·Dane CheasleyIan G Campbell
Oct 24, 2019·Nature Communications·Felix GrassmannKamila Czene
Feb 6, 2017·Breast Cancer Research and Treatment·Katharina HollandNico Karssemeijer
Nov 3, 2020·Breast Cancer Research and Treatment·Xueying HuEmily B Ambinder
Jan 25, 2021·European Radiology·Kristina LångIngvar Andersson
Nov 25, 2021·Cancer Causes & Control : CCC·Marta Hernández-GarcíaDolores Salas

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