A comparison of conventional spin-echo and fast spin-echo in the detection of multiple sclerosis

Journal of Magnetic Resonance Imaging : JMRI
W B PatolaS S Lingawi

Abstract

Fast spin-echo (FSE) pulse sequences enable T2-weighted imaging in a fraction of the time required for T2-weighted conventional spin-echo (CSE) imaging. Due to concerns that the altered contrast characteristics of FSE may interfere with the visualization of multiple sclerosis (MS) lesions, the sensitivity of T2-weighted FSE sequences was compared to comparably weighted CSE sequences in the imaging of the brain in 100 patients with clinically suspected MS. The proton-density FSE sequence revealed more MS lesions than its CSE counterpart, while the T2-weighted CSE sequences were found to be more sensitive than the T2-weighted FSE sequence. Contrast-to-noise ratios and signal-to-noise ratios compared favorably between sequences. Overall, there was little difference in the specificity between FSE and CSE in the diagnosis of MS. The higher sensitivity and the reduction in time attainable through the use of FSE warrants its replacement of CSE when imaging the brain in patients with clinically suspected MS. J. Magn. Reson. Imaging 2001;13:657-667.

References

Nov 1, 1992·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R T Constable, J C Gore
Jan 1, 1992·Magnetic Resonance Imaging·R T ConstableJ C Gore
Jan 1, 1990·Magnetic Resonance Imaging·R V MulkernF A Jolesz
Mar 10, 1990·BMJ : British Medical Journal·A J ThompsonW I McDonald
Sep 1, 1989·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·H B LarssonJ Olesen
Oct 1, 1989·Radiology·L KaufmanD A Ortendahl
Jul 1, 1988·Magnetic Resonance Imaging·J Hennig, H Friedburg
Jun 1, 1983·Annals of Neurology·S A LukesD Norman
May 1, 1994·The British Journal of Radiology·J M HawnaurI Isherwood
Apr 1, 1997·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·M RovarisM Filippi
Nov 24, 1999·European Journal of Radiology·K TsuchiyaT Maehara

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Citations

Apr 23, 2002·NMR in Biomedicine
Oct 9, 2007·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Mohit NeemaRohit Bakshi
Oct 4, 2002·Magnetic Resonance Imaging·Eugene G KholmovskiDennis L Parker
Jun 25, 2003·Investigative Radiology·Nancy L SicotteJohn C Mazziotta
Jul 9, 2010·Neurología : publicación oficial de la Sociedad Española de Neurología·A RoviraJ M Prieto
Jul 20, 2005·Journal of Magnetic Resonance Imaging : JMRI·Lisa L CookStephen J Karlik
May 17, 2006·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Jaime E SageCheryl Dingus
Jun 5, 2002·Current Opinion in Neurology·Frederik Barkhof
Mar 24, 2021·Magnetic Resonance Imaging·Li Sze Chow, Martyn N J Paley

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