A comparison of cost per case detected of screening strategies for Type 2 diabetes and impaired glucose regulation: modelling study.

Diabetes Research and Clinical Practice
Kamlesh KhuntiMelanie J Davies

Abstract

To determine a cost per case detected for different screening strategies for both Type 2 diabetes alone and in combination with impaired glucose regulation. Bayesian framework modelling study using data from the ADDITION-Leicester screening study in UK multi-ethnic primary care setting. There were 5794 people aged 40-75 years (77.4% white European; 22.6% south Asian) without previously known diabetes. We compared 212 screening strategies including blood tests, a computer practice data score and a risk score, as part of a multi-stage process that all used an oral glucose tolerance test as the diagnostic test. Simulation models were created using sensitivity estimates for the expected cost per case. The estimated costs per case identified for the 18 most sensitive strategies varied from £457 to £1639 (€526-1886, for £1=€1.15) for diabetes and £148-913 (€170-1050) for both diabetes and impaired glucose regulation. The lowest costing diabetes strategies ranged from £457 to £523 (€526-601) involving a two-stage screening strategy, a non-invasive risk stratifying tool followed by a blood test, producing sensitivities ranging from 67.1 to 82.4%. Screening a population using a non-invasive risk stratification tool followed by a screeni...Continue Reading

References

Jul 1, 1992·Diabetes Care·M I HarrisM W Knuiman
Mar 1, 2003·Diabetes Care·Jaana Lindström, Jaakko Tuomilehto
Jan 30, 2004·Diabetes Care·Stephen ColagiuriUNKNOWN AusDiab
Apr 28, 2010·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·B PaulweberT Yilmaz
Apr 28, 2010·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·J LindströmT Yilmaz
Jul 27, 2010·Diabetic Medicine : a Journal of the British Diabetic Association·L J GrayM J Davies
Nov 15, 2011·Diabetes Research and Clinical Practice·David R WhitingJonathan Shaw

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Citations

Jan 17, 2013·Diabetes Care·M Angelyn BethelRury R Holman
Jun 12, 2012·Diabetes Research and Clinical Practice·Stephen Colagiuri
Jul 6, 2015·Journal of Clinical Epidemiology·Gimon de GraafErik Buskens
Feb 25, 2015·Diabetes Research and Clinical Practice·Elroy J AguiarRobin Callister
Apr 4, 2014·Diabetes Research and Clinical Practice·Shaun R BarberLaura J Gray
Jul 15, 2016·Preventive Medicine Reports·I GroenenbergA M Stiggelbout
Oct 6, 2016·Journal of Diabetes Research·Naina PatelKamlesh Khunti
Oct 12, 2016·Primary Care Diabetes·Noël Christopher BarengoJaakko Tuomilehto
Oct 19, 2016·The Journal of Cardiovascular Nursing·James M Muchira, Eileen M Stuart-Shor
Aug 31, 2018·Acta Diabetologica·Juan ChenZilin Sun
Sep 11, 2020·International Journal of Dentistry·Alagesan Chinnasamy, Marjory Moodie
Jul 27, 2017·Diabetic Medicine : a Journal of the British Diabetic Association·S R BarberL J Gray

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