A comparison of doxorubicin and COP for maintenance of remission in cats with lymphoma

Journal of Veterinary Internal Medicine
A S MooreD A L'Heureux

Abstract

Thirty-eight cats with lymphoma were treated with vincristine, cyclophosphamide, and prednisone (COP). They were randomized at entry to receive maintenance chemotherapy consisting of either single-agent doxorubicin or continued COP therapy, starting on week 4 of treatment and continuing for 6 months or until relapse. Eighteen cats achieved complete clinical remission after COP induction chemotherapy. The median remission duration for 11 cats continuing to receive COP was 83 days, which was significantly shorter than for 7 cats that received doxorubicin (281 days). Thus, doxorubicin should be considered a well-tolerated and efficacious agent for the maintenance of remission in cats with lymphoma.

Citations

Sep 11, 2007·Journal of Feline Medicine and Surgery·Sophia TzannesLaura Blackwood
Nov 1, 2008·Journal of Feline Medicine and Surgery·Karen T OberthalerKarin U Sorenmo
Aug 19, 1999·Australian Veterinary Journal·A E Peaston, J E Maddison
Feb 22, 2008·Journal of Veterinary Internal Medicine·A G HaddenP Morrissey
Mar 4, 2008·Journal of Veterinary Internal Medicine·D SimonI Nolte
Nov 6, 2004·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Meg Sutherland-SmithPatrick Morris
Dec 4, 2012·Viruses·Katrin Hartmann
Feb 1, 2014·Journal of the American Veterinary Medical Association·K Tomo WiggansDavid J Maggs
Sep 11, 2001·Australian Veterinary Journal·L J GaborP J Canfield
Aug 3, 2011·Veterinary Immunology and Immunopathology·Katrin Hartmann
Apr 14, 2011·The Veterinary Clinics of North America. Small Animal Practice·Tracy Gieger
Nov 7, 2009·The Journal of Small Animal Practice·S S TaylorJ M Dobson
Nov 20, 2012·Journal of Veterinary Internal Medicine·E L KrickK U Sorenmo
Jul 11, 2003·The Veterinary Clinics of North America. Small Animal Practice·Timothy M Fan
Oct 14, 2003·The Veterinary Clinics of North America. Small Animal Practice·Keith P Richter
Aug 15, 2015·Redox Report : Communications in Free Radical Research·Nathieli B BottariAleksandro S Da Silva
Oct 1, 2016·The Veterinary Journal·Maria Teresa MandaraPietro Calò
Sep 8, 2009·Topics in Companion Animal Medicine·Ruthanne Chun
Jan 11, 2011·Journal of Feline Medicine and Surgery·Dorothy L ParshleyRavinder S Dhaliwal
Jul 25, 2000·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·V E ValliA Moore
Apr 23, 2013·Journal of Feline Medicine and Surgery·Antony Moore
Mar 1, 2012·Journal of Feline Medicine and Surgery·Vanessa R Barrs, Julia A Beatty
Mar 1, 2012·Journal of Feline Medicine and Surgery·Vanessa R Barrs, Julia A Beatty
Aug 16, 2017·Journal of Feline Medicine and Surgery·Zachary CrouseLinda Kidd
Feb 12, 2002·Australian Veterinary Journal·R MalikP J Canfield
May 31, 2003·Journal of Veterinary Internal Medicine·Janet K CarrerasKarin U Sørenmo
Jan 9, 2007·Journal of the American Animal Hospital Association·Chelsea B GreenbergMichael D Lucroy
Dec 17, 2020·The Journal of Small Animal Practice·L EconomuD Brodbelt
Jan 20, 2021·Journal of Feline Medicine and Surgery·Ashlyn G WilliamsKenneth E Lamb

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