A comparison of experimental compressive axial loading testing with a numerical simulation of topologically optimized cervical implants made by selective laser melting.

Journal of Biotechnology
Marek SchnitzerAndrej Somoš

Abstract

In recent years, the number of cervical interventions has increased. The stress shielding effect is a serious complication in cervical spine interventions. Topological optimization is based on finite element method structural analysis and numerical simulations. The generated design of cervical implants is made from Ti6Al4V powder by selective laser melting while the optimized cage is numerically tested for compressive axial loading and the results are compared with experimental measurement. Additive manufacturing technologies and new software possibilities in the field of structural analysis, which use the finite element method tools, help to execute implant topological optimization that is useful for clinical practice. The inner structures of the implant would be impossible to make by conventional manufacturing technologies. The resulting implant design, after modification, must fulfill strict application criteria for the area of cervical spine with respect to its material and biomechanical properties. The aim of this work was to alter the mechanical properties of the cervical intervertebral cage to address the clinical concern of the stress shielding effect by topological optimization. A methodology of cervical implant compre...Continue Reading

References

Jan 24, 2006·Medical Engineering & Physics·Zheng-Cheng ZhongChung-huang Yu
Nov 17, 2007·Bone·Vincent A StadelmannDominique P Pioletti
Oct 1, 2010·Clinical Orthopaedics and Related Research·M ScholzF Kandziora
Dec 20, 2012·Revista da Associação Médica Brasileira·UNKNOWN Brazilian Society of NeurosurgeryUNKNOWN Brazilian Society of Rheumatology
Apr 25, 2015·BMC Musculoskeletal Disorders·Elizabeth ChongWilliam R Walsh
Jul 5, 2016·World Neurosurgery·Ran HarelNachshon Knoller
Jul 25, 2017·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Scott SeamanPatrick W Hitchon
Jan 3, 2018·Orthopaedics & Traumatology, Surgery & Research : OTSR·N BocahutJ Allain
Mar 13, 2018·The Spine Journal : Official Journal of the North American Spine Society·Ron N AlkalayMichael W Groff

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of the Mechanical Behavior of Biomedical Materials
P K TomaszewskiN Verdonschot
Medical & Biological Engineering & Computing
Gabriella EpastoEugenio Guglielmino
Journal of the Mechanical Behavior of Biomedical Materials
Miguel CastilhoPaulo R Fernandes
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Sajad ArabnejadDamiano Pasini
© 2021 Meta ULC. All rights reserved