A comparison of longitudinal measurements in the spine and proximal femur using lunar and hologic instruments

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
N A PocockJ Freund

Abstract

Absolute values of bone mineral density (BMD), using dual-energy X-ray absorptiometry (DXA), differ between instruments from different manufacturers. Despite these differences, the rates of change calculated from serial measurements on different densitometers have been assumed to be comparable. We compared the change in BMD in 34 subjects in the lumbar spine and at the standard sites in the proximal femur, from measurements performed using a Lunar DPX-L and a Hologic QDR-1000. Measurements were obtained on the same day, and repeated on the same day, on both machines after a mean interval of 4.8 years (range 4.1-6.3 years). There were strong positive correlations between the percentage change in BMD calculated using the two machines in the lumbar spine, trochanteric region, and total proximal femur: r = 0.82, 0.84, and 0.73, respectively (p < 0.0001 at all sites). In the femoral neck and in Ward's triangle, the correlations were not as high: r = 0.55 (p = 0.003) and 0.43 (p = 0.028), respectively. At all sites, despite the significant correlations, the agreement between the two densitometers was not high and there may be significant errors in individual subjects if one uses measurements from one densitometer to predict the chang...Continue Reading

References

Sep 1, 1992·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·N A PocockJ A Eisman
Apr 18, 1991·The New England Journal of Medicine·C C JohnstonL J Melton
Feb 1, 1995·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J PearsonF Galan
Oct 1, 1994·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·H K GenantC Van Kuijk
Nov 1, 1995·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·N F Peel, R Eastell
Mar 15, 1997·Annals of Internal Medicine·L G Raisz

❮ Previous
Next ❯

Citations

Jan 21, 2010·Journal of Bone and Mineral Metabolism·Krista CasazzaJose R Fernandez
Jul 11, 2006·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J A ShepherdH K Genant
Aug 2, 2005·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Asma ArabiGhada El-Hajj Fuleihan
May 4, 2004·Obstetrics and Gynecology·Abbey B BerensonAngelyn Thomas
Jun 27, 2019·Nutrients·Kaiser WaniNasser M Al-Daghri
Nov 4, 1998·Medical Physics·J F SeelyG E Holland

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
N F Peel, R Eastell
Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Nicola J CrabtreeJ G Truscott
Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry
M A LaskeyAnn Prentice
© 2021 Meta ULC. All rights reserved