PMID: 8486019May 1, 1993

A comparison of manual to mechanical chest percussion for clearance of alveolar material in patients with pulmonary alveolar proteinosis (phospholipidosis)

Chest
W E HammonA J Cucchiara

Abstract

To our knowledge, there are no studies that compare the effectiveness of manual chest percussion (MN), mechanical chest percussion (MC), and no percussion (NP) for removing the proteinaceous material found in the alveoli of patients with pulmonary alveolar proteinosis (PAP) while undergoing whole-lung bronchopulmonary lavage (BPL). We analyzed the optical densities (OD) of 27 bottles of effluent from three BPLs of a patient with PAP. One technique was used per bottle. The order of techniques was balanced within each nine-bottle series and among the three BPLs. The mean OD for MN (0.933 +/- 0.494) was significantly superior to MC (0.477 +/- 0.265) (p < 0.0005) and NP (0.318 +/- 0.242) (p < 0.0001). We conclude that MN is superior to MC and NP and increases the therapeutic results of BPL for PAP.

References

Sep 27, 2001·Anesthesiology Clinics of North America·J S Bussières
Oct 6, 2012·Respirology : Official Journal of the Asian Pacific Society of Respirology·Steffen LethOle Hilberg
Jul 18, 2002·American Journal of Respiratory and Critical Care Medicine·John F Seymour, Jeffrey J Presneill
Sep 11, 2012·Multidisciplinary Respiratory Medicine·Ilaria CampoMaurizio Luisetti
Sep 8, 2004·Treatments in Respiratory Medicine·Saiprakash B VenkateshiahM S Kavuru
Nov 2, 2005·The Veterinary Clinics of North America. Small Animal Practice·Dianne DunningNicole Ehrhart
Dec 17, 2014·Revue des maladies respiratoires·S JouneauP Delaval
Oct 24, 2015·BioMed Research International·Tomas Vymazal, Martina Krecmerova
Jul 15, 2015·Journal of Bronchology & Interventional Pulmonology·Basem B AbdelmalakMarc J Popovich
Jul 22, 2010·Therapeutic Advances in Respiratory Disease·Maurizio LuisettiBruce C Trapnell
Mar 24, 2009·American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses·DaiWai M OlsonCarmelo Graffagnino
Jul 21, 2020·Breathe·Andrew Bush, Rishi Pabary
Aug 19, 2006·Chronic Respiratory Disease·O C Ioachimescu, M S Kavuru
Mar 9, 2017·Journal of Medical Case Reports·Janith GalhenageBandu Gunasena
May 1, 2011·Experimental and Therapeutic Medicine·Nalan Demır FiratNeslıhan Alkiş

Citations

Sep 15, 1979·British Medical Journal·K A FlowerJ Burgess
Jun 1, 1987·Mayo Clinic Proceedings·U B PrakashH M Marsh
Jun 5, 1958·The New England Journal of Medicine·S H ROSENA A LIEBOW

Related Concepts

Percussion
Lung
Alveolar
Bronchoalveolar Lavage
Anterior Thoracic Region
Body Fluids
Lung Diseases
Chest
Dental Percussion Procedure
Douching Procedure

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