A comparison of patient-controlled and fixed schedule analgesia after orthognathic surgery

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
D S PreciousP McGrath

Abstract

The purpose of this prospective study was to compare the effectiveness of patient-controlled intravenous (i.v.) opioid analgesic administration (PCA) with fixed schedule and dosage oral/rectal administration of naproxen, and opioid analgesics intramuscularly/orally as needed (i.m./p.o. prn) for postoperative analgesia over a period of 48 to 56 hours after surgery. There were 75 orthognathic patients aged 25.73 +/- 8.01 years, subdivided into three study groups of 25: codeine group (8 males, 17 females); naproxen group (5 males, 20 females) and PCA group (8 male, 17 females). The degree of analgesia was assessed every 4 hours from 8:00 AM to 8:00 PM hours on days 1 and 2 postsurgery using a visual analog scale (VAS). Mean daily and mean overall VAS scores were treated as parametric data and were analyzed accordingly. Mean daily VAS scores also were categorized as comfort days when mean scores were less than 3.0 cm, and as discomfort days when mean scores were equal to or greater than 3.0 cm. ANOVA were used to analyze patient demographics, pain scores, surgical time, fentanyl used during general anaesthesia, analgesic morphine equivalents, and vital signs. Chi-square tests were used to analyze sex, comfort (discomfort) days, and...Continue Reading

References

Apr 1, 1977·Clinical Pharmacology and Therapeutics·S S BloomfieldJ Mitchell
Jul 1, 1978·Clinical Pharmacology and Therapeutics·D R StanskiE Lowenstein
Oct 9, 1976·British Medical Journal·J M Smith, J E Utting
Nov 1, 1976·Anaesthesia·S I RevillM I Hogg
Jun 1, 1975·Clinical Pharmacology and Therapeutics·B A BerkowitzS Spector
Aug 14, 1975·European Journal of Clinical Pharmacology·C R JoyceR M Mason
Apr 1, 1976·Journal of Clinical Pharmacology·J P DesagerC Harvengt
May 1, 1991·Oral Surgery, Oral Medicine, and Oral Pathology·V Frost, G Peterson
Oct 1, 1990·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·T J WasylakM E Jeans
Jan 1, 1990·Journal of Advanced Nursing·E C Carr
Aug 1, 1989·British Journal of Anaesthesia·R W Mitchell, G Smith
Aug 1, 1989·Pediatric Clinics of North America·C B Berde
Sep 1, 1989·Journal of Pediatric Psychology·J P BushJ L Cockrell
Jul 1, 1989·Acta Anaesthesiologica Scandinavica·S DueholmE Lemvigh
Jul 1, 1987·The Australian and New Zealand Journal of Surgery·P J ChapmanK E Basford
Jan 1, 1987·Acta Anaesthesiologica Scandinavica. Supplementum·J J Bonica
Feb 1, 1988·Diseases of the Colon and Rectum·J M Albert, T M Talbott
Aug 1, 1985·American Journal of Orthodontics·C M FlanaryJ M Alexander
Nov 9, 1974·Lancet·E C Huskisson
Jan 1, 1973·Scandinavian Journal of Rheumatology. Supplement·J B StetsonL Lasagna
Jan 1, 1973·Scandinavian Journal of Rheumatology. Supplement·J Ruedy, W McCullough
Feb 1, 1973·Annals of Internal Medicine·R M Marks, E J Sachar
Sep 1, 1971·Canadian Anaesthetists' Society Journal·M Keeri-Szanto
Sep 1, 1970·Anesthesiology·W H ForrestM E Kienitz
Mar 1, 1983·Pain·L Mather, J Mackie
Sep 1, 1983·British Journal of Obstetrics and Gynaecology·N C SiddleM I Whitehead
Dec 1, 1983·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·C M Flanary, J M Alexander
Jun 1, 1982·Annals of Surgery·R L BennettW O Griffen
Jan 1, 1982·European Journal of Clinical Pharmacology·R A Seymour
Sep 1, 1995·The British Journal of Surgery·D NehraJ K Pye
Jul 1, 1995·British Journal of Anaesthesia·T J DunnG Jones
Jul 1, 1996·Anesthesia and Analgesia·J L PlummerK Tordoff
Jul 1, 1961·British Journal of Anaesthesia·J PARKHOUSEB R SIMPSON

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Citations

Jul 25, 2012·Anesthesia Progress·Soudeh CheginiDaljit K Dhariwal
Feb 9, 2017·Clinical Oral Investigations·Uilyong LeeHyun Kang
Jun 3, 2015·The Cochrane Database of Systematic Reviews·Ewan D McNicolJana Hudcova
Nov 17, 2020·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Dilek Günay CanpolatAhmet Emin Demirbaş
Jun 24, 2021·BioMed Research International·Han-Jen Hsu, Kun-Jung Hsu

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