PMID: 7026542Oct 1, 1981Paper

A comparison of phenelzine and imipramine in depressed inpatients

The Journal of Clinical Psychiatry
J R DavidsonR D Miller

Abstract

Phenelzine and imipramine were compared double-blind, in 43 depressed inpatients. A placebo week preceded drug treatment; this allowed early identification of placebo responders who did not therefore enter the study. After three weeks treatment, the two drugs were equally effective on Hamilton, Beck and SCL-90 measures of depression and anxiety. On the the SCL-90 scales of hostility and paranoia imipramine was more effective; in some patients phenelzine was associated with increased hostility. Measurement of MAO inhibition and plasma tricyclic levels indicated that adequate doses were generally used - (mean 81 mg/day phenelzine and 144 mg/day imipramine).

Citations

May 1, 1983·Journal of Affective Disorders·J Davidson, C Turnbull
Jul 1, 1986·American Family Physician·S Lippmann
Feb 1, 1986·Psychiatry Research·J Davidson, S Pelton

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.