Jul 31, 2012

A comparison of rectilinear and truncated exponential biphasic waveforms in elective cardioversion of atrial fibrillation: a prospective randomized controlled trial

Resuscitation
Charles D DeakinHo Ming Yuen

Abstract

Several different biphasic waveforms are used clinically, but few studies have compared their efficacy. The two main waveforms are the biphasic rectilinear (BR) and biphasic truncated exponential (BTE) waveforms, both of which have important differences, particularly at the extremes of transthoracic impedance. To compare the efficacy of two commonly used defibrillation waveforms in the elective cardioversion of atrial fibrillation. In a prospective randomized controlled study, sequential adult patients undergoing elective cardioversion for AF were recruited. Patients were randomized to receive synchronized defibrillation using either a BR or BTE waveform, both using a 50J, 100J, 150J, 200J, 200J selected energy escalating protocol. Failure to cardiovert after the fifth shock was classed as failed defibrillation. The power of this study was 80% with 5% significance level to detect a difference of 20% or greater between groups. Survival analysis was used to compare the total energy delivered to achieve successful cardioversion between groups. A total of 202 patients were recruited, of which data are complete for 199 (100 BR; 99 BTE). Median number of shocks to achieve cardioversion was 2 for the BR waveform and 3 for the BTE wave...Continue Reading

Mentioned in this Paper

Ventricular Fibrillation
Electric Impedance
Left Ventricular Structure
Randomized Controlled Trial (Publication)
Myocardium
Shock
Sinus - General Anatomical Term
Atrial Fibrillation
Cardiomyopathies
Obesity

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