PMID: 8970016Jun 1, 1996Paper

A comparison of six deconvolution techniques

Journal of Pharmacokinetics and Biopharmaceutics
F N MaddenR A Bates

Abstract

We present results for the comparison of six deconvolution techniques. The methods we consider are based on Fourier transforms, system identification, constrained optimization, the use of cubic spline basis functions, maximum entropy, and a genetic algorithm. We compare the performance of these techniques by applying them to simulated noisy data, in order to extract an input function when the unit impulse response is known. The simulated data are generated by convolving the known impulse response with each of five different input functions, and then adding noise of constant coefficient of variation. Each algorithm was tested on 500 data sets, and we define error measures in order to compare the performance of the different methods.

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Citations

Jan 12, 2013·Journal of Pharmacokinetics and Pharmacodynamics·Carl-Christer JohanssonRasmus Jansson-Löfmark
May 23, 2001·Advanced Drug Delivery Reviews·P Veng-Pedersen
Nov 7, 2003·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Frieder Langenbucher
Oct 23, 2008·Endocrine Reviews·Johannes D VeldhuisSteven M Pincus
Nov 9, 2007·Journal of Pharmaceutical Sciences·Clare GaynorJohn Davis
Feb 20, 2009·Journal of Pharmaceutical Sciences·Clare GaynorJohn Davis
Dec 17, 2004·Journal of Veterinary Pharmacology and Therapeutics·P L Toutain, A Bousquet-Mélou
Feb 17, 2009·Biometrical Journal. Biometrische Zeitschrift·Stephan Koehne-Voss, Iris Pigeot
Oct 26, 2012·Biopharmaceutics & Drug Disposition·Maziar KakhiJason Chittenden
Sep 29, 2004·Toxicology Letters·Sanja KezicMaarten M Verberk
Jul 24, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Yuanmu DengJay L Zweier
Apr 12, 2013·Endocrine Reviews·Ferdinand Roelfsema, Johannes D Veldhuis
May 22, 2004·Physics in Medicine and Biology·Parminder S BasranDavid P Spencer
May 5, 2017·Frontiers in Bioengineering and Biotechnology·Magnus TrägårdhPeter Gennemark
Nov 3, 2017·Optics Express·A LucatR Pacanowski
Mar 12, 2019·Analytical Chemistry·Scott R GriffinGarth J Simpson
Aug 31, 2007·Theoretical Population Biology·Hans-Georg MüllerJames R Carey
May 12, 2006·The Journal of Physical Chemistry. a·Akos Bányász, Erno Keszei

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