A comparison of stages IB1 and IB2 cervical cancers treated with radical hysterectomy. Is size the real difference?

Gynecologic Oncology
Teresa L RutledgeD Scott McMeekin

Abstract

To compare stages IB1 and IB2 cervical cancers treated with radical hysterectomy (RH) and to define predictors of nodal status and recurrence. Patients with stage IB cervical cancers undergoing RH between 1990 and 2000 were evaluated and clinicopathological variables were abstracted. The perioperative complication rate, estimated blood loss (EBL), and OR time were also tabulated. Variables were analyzed using X(2) and t tests. Disease-free survival (DFS) was calculated by Kaplan-Meier method. Multivariate analysis was performed via stepwise logistic regression. Cox-proportional hazards were used to identify independent predictors of recurrence. RH was performed on 109 stage IB1 and 86 stage IB2 patients. Mean age, EBL, and perioperative complication rates were similar. Overall, 38 patients (14 IB1 vs. 24 IB2) had positive nodes (P = 0.01) including 9 patients with positive para-aortic nodes (2 IB1 and 7 IB2). Parametrial involvement (PI) and outer 2/3 depth of invasion (DOI) were significantly more common in the IB2 tumors as well. Patients with IB2 disease received adjuvant radiation more frequently than IB1 patients (52% vs. 37%, P = 0.04). Univariate predictors of nodal status included lymphovascular space involvement (LVSI)...Continue Reading

References

Apr 30, 1994·International Journal of Radiation Oncology, Biology, Physics·P J EifelM J Oswald
Apr 14, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·W A PetersD S Alberts

❮ Previous
Next ❯

Citations

Jun 29, 2007·Journal of Clinical Pathology·E R NijhuisA G J van der Zee
Jul 3, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J-Y ParkJ-H Nam
Nov 18, 2015·Acta Obstetricia Et Gynecologica Scandinavica·Marloes DerksMarrije R Buist
Apr 4, 2013·Taiwanese Journal of Obstetrics & Gynecology·Jerry Cheng-Yen LaiKung-Liahng Wang
Jun 21, 2007·The Journal of Obstetrics and Gynaecology Research·Jong-Min LeeChan-Yong Park
Sep 18, 2010·The Journal of Obstetrics and Gynaecology Research·Yanna ZhangXueming Sun
Jun 6, 2006·International Journal of Radiation Oncology, Biology, Physics·Akila N ViswanathanChristopher P Crum
May 12, 2006·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·J M LeeC Y Park
Apr 23, 2015·Best Practice & Research. Clinical Obstetrics & Gynaecology·Kailash Narayan, Ming Yin Lin
Nov 3, 2009·American Journal of Obstetrics and Gynecology·Nisha BansalJason D Wright
Apr 25, 2014·Journal of Gynecologic Oncology·Kanyarat KatanyooBusaba Supawattanabodee
Mar 18, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Gunjal GargRobert T Morris
May 2, 2006·Obstetrics and Gynecology·David H Moore
May 3, 2013·Obstetrics and Gynecology·Neville F HackerMichael Jackson
Feb 9, 2013·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Samith SandadiNadeem R Abu-Rustum
Oct 12, 2012·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·László UngárUNKNOWN FACOG Committee on Practice Bulletins
Oct 7, 2018·International Journal of Clinical Oncology·Yasuhiko EbinaDaisuke Aoki
Apr 9, 2010·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·P SuprasertJ Sae-Teng
May 21, 2021·Nigerian Journal of Surgery : Official Publication of the Nigerian Surgical Research Society·Nikhil MehtaElroy Saldanha

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.